ID   R6CEM6_9FIRM            Unreviewed;       246 AA.
AC   R6CEM6;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Sortase family protein {ECO:0000313|EMBL:CDA71374.1};
GN   ORFNames=BN718_00613 {ECO:0000313|EMBL:CDA71374.1};
OS   Ruminococcus sp. CAG:579.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=1262963 {ECO:0000313|EMBL:CDA71374.1, ECO:0000313|Proteomes:UP000018387};
RN   [1] {ECO:0000313|EMBL:CDA71374.1, ECO:0000313|Proteomes:UP000018387}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:579 {ECO:0000313|Proteomes:UP000018387};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA71374.1}.
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DR   EMBL; CBCK010000010; CDA71374.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6CEM6; -.
DR   STRING; 1262963.BN718_00613; -.
DR   Proteomes; UP000018387; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd05828; Sortase_D_1; 1.
DR   Gene3D; 2.40.260.10; Sortase; 1.
DR   InterPro; IPR005754; Sortase.
DR   InterPro; IPR041999; Sortase_D_1.
DR   InterPro; IPR023365; Sortase_dom-sf.
DR   NCBIfam; TIGR01076; sortase_fam; 1.
DR   Pfam; PF04203; Sortase; 1.
DR   SUPFAM; SSF63817; Sortase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018387};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        24..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   ACT_SITE        160
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT   ACT_SITE        217
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ   SEQUENCE   246 AA;  27752 MW;  E338677A6F831130 CRC64;
     MKKRSLDAER SAEKRGRGTS SNRVLRTITF VLTPFLMSAL LFGVVALAAA KPFAAAKPYV
     NIVFNNDDNS IKNARTINKY RDDNAPVQKK EVEDGATGEK HTMVYPYYGD KYATLNCEAA
     GMNDIPVYSG TTNDILAEGA GWYNGSVYIG HVGNVVLAGH NHTYFYNLPK CKKGDEVTLE
     TSYVKQTYMV TDIEIFHEDD QTYVRPTDDD RLTMYTCWNN GMLGMSEYRI AVICELTDRE
     WKEVEE
//