ID   R6DHR5_9BACE            Unreviewed;       491 AA.
AC   R6DHR5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=O-Glycosyl hydrolase family 30 {ECO:0000313|EMBL:CDA83826.1};
GN   ORFNames=BN772_02290 {ECO:0000313|EMBL:CDA83826.1};
OS   Bacteroides sp. CAG:754.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1262750 {ECO:0000313|EMBL:CDA83826.1, ECO:0000313|Proteomes:UP000017906};
RN   [1] {ECO:0000313|EMBL:CDA83826.1, ECO:0000313|Proteomes:UP000017906}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:754 {ECO:0000313|Proteomes:UP000017906};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC       {ECO:0000256|ARBA:ARBA00005382, ECO:0000256|RuleBase:RU361188}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA83826.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CBCP010000106; CDA83826.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6DHR5; -.
DR   Proteomes; UP000017906; Unassembled WGS sequence.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR033452; GH30_C.
DR   InterPro; IPR001139; Glyco_hydro_30.
DR   InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR   PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF02055; Glyco_hydro_30; 2.
DR   Pfam; PF17189; Glyco_hydro_30C; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU361188};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361188};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017906};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..491
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004403978"
FT   DOMAIN          66..173
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
FT   DOMAIN          220..422
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
FT   DOMAIN          436..488
FT                   /note="Glycosyl hydrolase family 30 beta sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF17189"
SQ   SEQUENCE   491 AA;  56689 MW;  EA1824DFE131B410 CRC64;
     MNLKKLCTLG TLLAFFSSIY AQSFIWISST DNNVWKEAKI RLQADSQNIP LLSVDGTENI
     QIFKKWGTCF NELGWDALNM LPLKEQDAVL NNLFSPDGDL RFSMGRIPMN ANDYARNWYS
     CDEVPGDFRL KYFNINRDKT TLIPYIKRVQ RINSDMTFWA SPWSPPSWMK VNHYYSVRSK
     AEVNQLPVKH EIALYEGADN VDKTFYPKQV AVNDYFIQDT RYLQAYANYF CKFVSAYQEE
     GVTISRVMFQ NEPWAYSIYP ACAWTPEGII RFNVEYFAPT IKKLHPDVQV YLGTLNTNRI
     ELVEKVLSDP RMKDAVEGVG FQWWGGQILP EIRKKYPNYK YMQTESECGS GTFDWKAAEH
     TFNLISHYLG NGCEEYTFWN AILCDAGTSG WGWKQNALIR VDSKTASVTY TPEYYAVKHF
     SNKVVSGTKV LQYKAKGEDK LPVVIFLTPE KRYLVVAANF NDEPKNLTVK LGDKFLDVTL
     KAHSFNTFSM K
//