ID   R6DYI6_9FIRM            Unreviewed;       459 AA.
AC   R6DYI6;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Penicillin-binding protein transpeptidase domain protein {ECO:0000313|EMBL:CDA89974.1};
GN   ORFNames=BN553_01173 {ECO:0000313|EMBL:CDA89974.1};
OS   Firmicutes bacterium CAG:238.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1263011 {ECO:0000313|EMBL:CDA89974.1, ECO:0000313|Proteomes:UP000018260};
RN   [1] {ECO:0000313|EMBL:CDA89974.1, ECO:0000313|Proteomes:UP000018260}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:238 {ECO:0000313|Proteomes:UP000018260};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDA89974.1}.
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DR   EMBL; CBCS010000050; CDA89974.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6DYI6; -.
DR   Proteomes; UP000018260; Unassembled WGS sequence.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018260}.
FT   DOMAIN          148..450
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   459 AA;  48367 MW;  6511830CD150F71A CRC64;
     MKKLERRAFL CLALVAVLLA GLVFFIVRIE TNGADWATFY ANTHIYANGK LSVGSVYDRN
     GKLLLKNTSK GMRYNSDELI RRANLHSSGD PAANIATGAN VAFKSRMVGY NFVTGTGGLL
     KMGGSKVYLT VDAKVNRSAY EALSGRNGLV GVYNYKTGEI VCMVSTPSYD PGENGRNTLS
     NPLPGTYMNK LISGTLTPGS TFKLVTTAAA IEQIDGINKW IYKCTGSLAV GGDKITCPKV
     HGTMDIYGAL ANSCNCAYAT LAMELGGDVL AEYADSLQLT QSYDIDGIKS AAGTFNFDSA
     DVNIGWAGIG QFEDQLNPLS MMVYMGAIAG EGKAALPVLL SDESLIKKGA ELIGSDSAAG
     AAAGSVRLLS SETARTLSDM MRNNVKVTYG DGNYPGLSLH AKSGTAEVGT GKAPHSWFCG
     FAGDYAFIVC VENGGYGSSV AGPVANNVLQ YMKSEGCKF
//