ID R6E4L3_9FIRM Unreviewed; 196 AA.
AC R6E4L3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=bis(5'-nucleosyl)-tetraphosphatase (symmetrical) {ECO:0000256|ARBA:ARBA00012506};
DE EC=3.6.1.41 {ECO:0000256|ARBA:ARBA00012506};
GN ORFNames=BN710_01560 {ECO:0000313|EMBL:CDA92204.1};
OS Ruminococcus sp. CAG:563.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1262961 {ECO:0000313|EMBL:CDA92204.1, ECO:0000313|Proteomes:UP000018082};
RN [1] {ECO:0000313|EMBL:CDA92204.1, ECO:0000313|Proteomes:UP000018082}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:563 {ECO:0000313|Proteomes:UP000018082};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate = 2 ADP + 2
CC H(+); Xref=Rhea:RHEA:24252, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:58141, ChEBI:CHEBI:456216; EC=3.6.1.41;
CC Evidence={ECO:0000256|ARBA:ARBA00001682};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDA92204.1}.
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DR EMBL; CBCR010000102; CDA92204.1; -; Genomic_DNA.
DR AlphaFoldDB; R6E4L3; -.
DR STRING; 1262961.BN710_01560; -.
DR Proteomes; UP000018082; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR005249; YqeK.
DR NCBIfam; TIGR00488; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK; 1.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR35795:SF1; BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE, SYMMETRICAL; 1.
DR PANTHER; PTHR35795; SLR1885 PROTEIN; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CDA92204.1};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Reference proteome {ECO:0000313|Proteomes:UP000018082}.
FT DOMAIN 21..136
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 196 AA; 22032 MW; FC4D560F74C7B890 CRC64;
MSTWTDEKII TLIRSRLDDY RFNHSLNVAD SAKELAIRYG GDADKAYTAG LLHDVMKNAS
EEEQLGVLSE AGIELMPVER ANKKLWHAMA GAAYIKFVMG IDDREIIRAV RYHTTGRAGM
SLLEKIVYLA DYISAERNYN GVEDMRRLCE KDMDSAIEYA LVFGIPDLVS KGQVIHPDSI
DLYNEVIIKK QGGNSL
//
