ID   R6EJ52_9FIRM            Unreviewed;       462 AA.
AC   R6EJ52;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Glutamate synthase homotetrameric {ECO:0000313|EMBL:CDB00598.1};
GN   ORFNames=BN538_02243 {ECO:0000313|EMBL:CDB00598.1};
OS   Lachnospiraceae bacterium CAG:215.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1262985 {ECO:0000313|EMBL:CDB00598.1, ECO:0000313|Proteomes:UP000018007};
RN   [1] {ECO:0000313|EMBL:CDB00598.1, ECO:0000313|Proteomes:UP000018007}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:215 {ECO:0000313|Proteomes:UP000018007};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB00598.1}.
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DR   EMBL; CBCV010000344; CDB00598.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6EJ52; -.
DR   Proteomes; UP000018007; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR006004; SudA-like.
DR   NCBIfam; TIGR01316; gltA; 1.
DR   PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 2.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          32..62
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   462 AA;  49380 MW;  AEE0FDFD4470B3CE CRC64;
     MADVLKKVPV REQDPKVRAA NFEEVCLGYN QEEAMEEAAR CINCKNAKCI QGCPVAINIP
     GFIKEVKDGN IEEAYKVIGQ ASALPAICGR VCPQESQCEG QCIRGIKGEP ISIGKLERFV
     ADYALEHDIK PVGAEKTNGH KVAVIGSGPS GLTCAGDLAK LGYEVTVFEA LHELGGVLVY
     GIPEFRLPKQ KVVAKEIEKV KELGVKFETN VVIGKSTTID QLIEEEGFEA VFIGSGAGLP
     KFMGIPGENA NGVFSANEYL TRSNLMKAFD DNYDTPICAG TKVAVVGGGN VAMDAARTAL
     RLGAEVHIVY RRSEEELPAR VEEVHHAKEE GIIFDLLTNP KEILVDDKGN VTGMKVIKME
     LGEPDASGRR RPVEVPGSEF VIDVDTVIMS LGTSPNPLIS STTEGLEINK WKCIVADEES
     GKTSKEGVYA GGDAVTGAAT VILAMGAGKA AAKGIDEYLR DK
//