ID R6EMK2_9FIRM Unreviewed; 548 AA.
AC R6EMK2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=PhoU domain-containing protein {ECO:0000259|Pfam:PF01895};
GN ORFNames=BN538_02451 {ECO:0000313|EMBL:CDB01165.1};
OS Lachnospiraceae bacterium CAG:215.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1262985 {ECO:0000313|EMBL:CDB01165.1, ECO:0000313|Proteomes:UP000018007};
RN [1] {ECO:0000313|EMBL:CDB01165.1, ECO:0000313|Proteomes:UP000018007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:215 {ECO:0000313|Proteomes:UP000018007};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB01165.1}.
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DR EMBL; CBCV010000388; CDB01165.1; -; Genomic_DNA.
DR AlphaFoldDB; R6EMK2; -.
DR Proteomes; UP000018007; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005436; F:sodium:phosphate symporter activity; IEA:InterPro.
DR GO; GO:0044341; P:sodium-dependent phosphate transport; IEA:InterPro.
DR InterPro; IPR003841; Na/Pi_transpt.
DR InterPro; IPR004633; NaPi_cotrn-rel/YqeW-like.
DR InterPro; IPR038078; PhoU-like_sf.
DR InterPro; IPR026022; PhoU_dom.
DR NCBIfam; NF037997; Na_Pi_symport; 1.
DR NCBIfam; TIGR00704; NaPi_cotrn_rel; 1.
DR PANTHER; PTHR10010:SF46; SODIUM_PHOSPHATE COTRANSPORTER-RELATED; 1.
DR PANTHER; PTHR10010; SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED; 1.
DR Pfam; PF02690; Na_Pi_cotrans; 2.
DR Pfam; PF01895; PhoU; 2.
DR SUPFAM; SSF109755; PhoU-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 50..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 346..432
FT /note="PhoU"
FT /evidence="ECO:0000259|Pfam:PF01895"
FT DOMAIN 451..533
FT /note="PhoU"
FT /evidence="ECO:0000259|Pfam:PF01895"
FT COILED 473..500
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 548 AA; 59882 MW; 69A0C6FB4B0E9A29 CRC64;
MGITTIFLLL GGLGLFLFGM KLMSDGLEQV AGARMRSILE FFTKNRFVGM LVGILFTAVV
QSSSATTVMV VSFVNSGLMN LFQAAGVILG ANIGTTVTGQ LIAFNLSDVA PLFVIIGVVM
FMFCNKQNVK KIGVVILGFG ILFMGLSTMS GAMSSFKESP EVVSLLGSLT NPLMAILVGF
MITAILQSSS ATVGIVILMA SQGLLAFPIC FFLILGCNMG SCVSALLASI GGKKDAKRAA
WIHFLFNIIG SFVIFMILMI ALDPIADGIL TLSKGNVSRA VANAHTLIKI CEVFLLFPFM
GWVVKATYRI VPGEDVRSTD TYELKYIQPE GNVSPATAVV DGIHELQQMG ELARTNLKMS
MEALCEPDEK KIKAVCEQEA YIDFLNREIT DYLVKISELD LPIADAKILG GLFHVVNDIE
RIGDHAENFA EAAKERMEKQ IPFSEKAIRQ IREMAEMVTE VLDYALQMFS ERSTEHMKEV
LQLEEAVDQL ERKLQKAHVK RLTKGKCTPE ASMLYSDAIS GLERAADHAT NIAFAILEPE
DLSEEEEE
//
