ID R6ESM8_9FIRM Unreviewed; 593 AA.
AC R6ESM8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=PhoU domain-containing protein {ECO:0000259|Pfam:PF01895};
GN ORFNames=BN497_00499 {ECO:0000313|EMBL:CDB02910.1};
OS Firmicutes bacterium CAG:145.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263005 {ECO:0000313|EMBL:CDB02910.1, ECO:0000313|Proteomes:UP000018044};
RN [1] {ECO:0000313|EMBL:CDB02910.1, ECO:0000313|Proteomes:UP000018044}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:145 {ECO:0000313|Proteomes:UP000018044};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB02910.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CBCX010000084; CDB02910.1; -; Genomic_DNA.
DR AlphaFoldDB; R6ESM8; -.
DR STRING; 1263005.BN497_00499; -.
DR Proteomes; UP000018044; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005436; F:sodium:phosphate symporter activity; IEA:InterPro.
DR GO; GO:0044341; P:sodium-dependent phosphate transport; IEA:InterPro.
DR InterPro; IPR003841; Na/Pi_transpt.
DR InterPro; IPR038078; PhoU-like_sf.
DR InterPro; IPR026022; PhoU_dom.
DR NCBIfam; NF037997; Na_Pi_symport; 1.
DR PANTHER; PTHR10010:SF46; SODIUM_PHOSPHATE COTRANSPORTER-RELATED; 1.
DR PANTHER; PTHR10010; SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED; 1.
DR Pfam; PF02690; Na_Pi_cotrans; 2.
DR Pfam; PF01895; PhoU; 2.
DR SUPFAM; SSF109755; PhoU-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018044};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 361..447
FT /note="PhoU"
FT /evidence="ECO:0000259|Pfam:PF01895"
FT DOMAIN 475..549
FT /note="PhoU"
FT /evidence="ECO:0000259|Pfam:PF01895"
SQ SEQUENCE 593 AA; 64354 MW; AE3CDF9F09941F52 CRC64;
MNIFSVISLL GGLAMFLYGM EVMGAGLKNA SGPALKKALG KATQNVVFGV ITGMLVTAVI
QSSTATIVLA VGLISAGILT LKQAVGIVMG ANIGTTVTAQ IIRLMDIDSG GNIALEFIKP
STLAPLSMFV GILLIMFIKL PNSKTKGEIF MGFGVLFSGI INMTAAVSPL SESQMFVDLM
AKFSNQPILS ILIGMVLTVV VQSSSAMVGI LQALSATGAI TFNLVYPMIM GINLGTCVVT
LFICSIGSSK DAKRIGIVHI LFNTIGTFLF MIAMTLIHSL GGFPNLWDSV VNSGSIANFQ
TLFNLITAIV LVPFAGKLVD ASQRIIKVTK MDEEDRADLE VPDEKLFEVP EMAISEAGKA
IAHMGEVALK NLKRSCKLLY VYDENRVSVI NENEDNMDLF TDSMDTYLVN LSKFVETDSD
SQRVSTMMQT STNFERIGDH AMNIMEVAQN IRGGKLEFSD SAKEELEKVK DAIFEITAIT
VEAFSSMDSD IAKRVEPLEE VIDDMVITLK NRHIERLKRG ECTTATGMAF VDALTNLERV
ADQCSNVALL ILGEKYKEIM GNHHAYVREL HKGGDPIYNE ELSKRKEQFL VGL
//
