ID R6EYD3_9BACT Unreviewed; 719 AA.
AC R6EYD3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Penicillin-binding protein transpeptidase domain protein {ECO:0000313|EMBL:CDB05728.1};
GN ORFNames=BN691_00497 {ECO:0000313|EMBL:CDB05728.1};
OS Prevotella sp. CAG:520.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1262929 {ECO:0000313|EMBL:CDB05728.1, ECO:0000313|Proteomes:UP000018359};
RN [1] {ECO:0000313|EMBL:CDB05728.1, ECO:0000313|Proteomes:UP000018359}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:520 {ECO:0000313|Proteomes:UP000018359};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB05728.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CBCY010000162; CDB05728.1; -; Genomic_DNA.
DR AlphaFoldDB; R6EYD3; -.
DR STRING; 1262929.BN691_00497; -.
DR Proteomes; UP000018359; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR PROSITE; PS51178; PASTA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000018359};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 661..719
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 719 AA; 79761 MW; E670C611DAB7D42D CRC64;
MSKFDSKKVM PRYAFIAVIM TLVAISVLGK TLYIMTAKRA YWEEVADRVK VDSLKTQPMR
GNILSCDGQL MASSLPQYNI FMDFKALREA KKDTLFCEKI DSICTGLNAI FPDRTAAEFK
KHLMEGFEKN KRHWPVWNRR INYSTFSEVR RLPVFRLKTN MGGFHWEEHN ARRLAYGSLA
GRTIGKMFGA KDTAQCGLEL SYDSLLRGVE GIRHRRKVLN RYLDITDTPP ENGADIVTTI
DVSMQDLAER ALLKELRLIN ANVGVAIVME VKTGDIKAIV NMTKCDDDDY HEIKNHAISD
LLEPGSVFKT ASIMVALDDG VVDTTYRVET AGGVWPMYGR EMKDHNWRRG GYGMLTLPQT
LMVSSNIGVS RIIDDHYHNT PEKFVQGIYR LGLADDLHIP LQGASPARIR MPKKDSRGKQ
YVNWSKTTLP WMSIGYETQV PPISTLTFYN AIANGGKMVA PRFVKAVMKD GVVIKEFDPV
VLREQIAKES TIKKITTILE HVVSQGLGKK AGSQSFLVAG KTGTAQISKG AAGYKSGQMN
YLLSFAGFFP AYEPRYSCIV CIQKSGLPAS GGGMSGVVFH DIAEGIMAQS LKLEASDARD
SLSVLIPQVK SGNVLAASYV LEHLGVKQRT DWDGSYLNGN PIWGRADESD RSIIQLKRVN
EGDKSVMPDV HGMGARDAVF LIESRGVKVR LTGRGKVTEQ SIGAGERIKK GMVCSLKLG
//
