ID   R6FLN2_9FIRM            Unreviewed;       279 AA.
AC   R6FLN2;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   RecName: Full=Ribosome biogenesis GTPase A {ECO:0000256|ARBA:ARBA00014898, ECO:0000256|PIRNR:PIRNR006230};
GN   ORFNames=BN497_00551 {ECO:0000313|EMBL:CDB02962.1};
OS   Firmicutes bacterium CAG:145.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1263005 {ECO:0000313|EMBL:CDB02962.1, ECO:0000313|Proteomes:UP000018044};
RN   [1] {ECO:0000313|EMBL:CDB02962.1, ECO:0000313|Proteomes:UP000018044}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:145 {ECO:0000313|Proteomes:UP000018044};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for a late step of 50S ribosomal subunit assembly.
CC       Has GTPase activity. {ECO:0000256|PIRNR:PIRNR006230}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR006230}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1
CC       subfamily. {ECO:0000256|PIRNR:PIRNR006230}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB02962.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CBCX010000087; CDB02962.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6FLN2; -.
DR   STRING; 1263005.BN497_00551; -.
DR   Proteomes; UP000018044; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   CDD; cd01856; YlqF; 1.
DR   Gene3D; 1.10.1580.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR023179; GTP-bd_ortho_bundle_sf.
DR   InterPro; IPR019991; GTP-bd_ribosome_bgen.
DR   InterPro; IPR016478; GTPase_MTG1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR03596; GTPase_YlqF; 1.
DR   PANTHER; PTHR45782; MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1; 1.
DR   PANTHER; PTHR45782:SF4; MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   PIRSF; PIRSF006230; MG442; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR006230};
KW   GTP-binding {ECO:0000256|PIRNR:PIRNR006230, ECO:0000256|PIRSR:PIRSR006230-
KW   1};
KW   Nucleotide-binding {ECO:0000256|PIRNR:PIRNR006230,
KW   ECO:0000256|PIRSR:PIRSR006230-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018044}.
FT   DOMAIN          14..175
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51721"
FT   BINDING         59..62
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006230-1"
FT   BINDING         127..132
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006230-1"
FT   BINDING         171
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006230-1"
SQ   SEQUENCE   279 AA;  31400 MW;  C28C2105668D9B93 CRC64;
     MDNINWYPGH MKKTRELIED SLKMVDLVIE VVDARIPVSS RNPIIDQLTR GKRRVIILNK
     SDLSDPSANE AWENRLKEEG NMVTAMNCMK GQGTKQLLKL LSSLQAEKNE GKIRKKPLRM
     MIVGVPNVGK SSLINRLTGR KSAKTGDRPG VTRGKQWLSL ESGMQLLDTP GILWPKFEDP
     RAGLNLAFCG SIKDEILDVS DLALELIKVL QDKYPRLLID RYKIEDIGDT PLETMEAIAK
     RRGFILAGKR IDYERCARTL LDEFRGGVIG NITLETADD
//