ID R6FM28_9FIRM Unreviewed; 446 AA.
AC R6FM28;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=N-acetylmuramoyl-L-alanine amidase {ECO:0000313|EMBL:CDB13055.1};
GN ORFNames=BN525_00961 {ECO:0000313|EMBL:CDB13055.1};
OS Eubacterium sp. CAG:192.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1262883 {ECO:0000313|EMBL:CDB13055.1, ECO:0000313|Proteomes:UP000017943};
RN [1] {ECO:0000313|EMBL:CDB13055.1, ECO:0000313|Proteomes:UP000017943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:192 {ECO:0000313|Proteomes:UP000017943};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB13055.1}.
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DR EMBL; CBDB010000255; CDB13055.1; -; Genomic_DNA.
DR AlphaFoldDB; R6FM28; -.
DR STRING; 1262883.BN525_00961; -.
DR Proteomes; UP000017943; Unassembled WGS sequence.
DR GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:InterPro.
DR GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR CDD; cd02696; MurNAc-LAA; 1.
DR Gene3D; 2.10.270.10; Cholin Binding; 2.
DR Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 1.
DR InterPro; IPR018337; Cell_wall/Cho-bd_repeat.
DR InterPro; IPR002508; MurNAc-LAA_cat.
DR PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR Pfam; PF01520; Amidase_3; 1.
DR Pfam; PF01473; Choline_bind_1; 3.
DR SMART; SM00646; Ami_3; 1.
DR SUPFAM; SSF69360; Cell wall binding repeat; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS51170; CW; 1.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..446
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004406043"
FT DOMAIN 154..288
FT /note="MurNAc-LAA"
FT /evidence="ECO:0000259|SMART:SM00646"
FT REPEAT 319..338
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REGION 35..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 50036 MW; DAF23027A1EAD875 CRC64;
MRKLKRTFYI GTTTFLLGLG IVFSNNVLAA VEQETTTQVE TTTVEETTPN ETTPPEQTTP
AETTKPQETT TVEKYTESNL SPVKSKIILL DPGHCKVHIG AHGNGLKEEI ITLDIGLACR
DYLNKFSDVT VYMTRTNGNC LSTASLAGCL VARNNMAKRL DADFLVSLHI NSDPSPSRKG
ALLLSAYNSG YRTSVGIKTT KLGKKILDNL QLAGVYNGGF LLRKSNDYYY PNKARADYYS
IVREGIYNKI PSIIVEHGFI TNKSDCKKFL KTTAKRKKLG VADAKGIVTY YNLSKKNISG
TLNKKGKSTY YINSSGKKIT GWVKVNGRWY HFNSKNAKMD KGFITVGKNK FYLNSKTGVL
KTGWFIVKNK KYLAKGNGVI LRSKIYNDGV SSYYFNSKGY KKNGWVTYKN ATYYFSKKKG
MLKGKQKIKK KYYRFSKKTG KLLSKR
//
