ID R6FU83_9BACT Unreviewed; 742 AA.
AC R6FU83;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BN691_00356 {ECO:0000313|EMBL:CDB05567.1};
OS Prevotella sp. CAG:520.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1262929 {ECO:0000313|EMBL:CDB05567.1, ECO:0000313|Proteomes:UP000018359};
RN [1] {ECO:0000313|EMBL:CDB05567.1, ECO:0000313|Proteomes:UP000018359}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:520 {ECO:0000313|Proteomes:UP000018359};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB05567.1}.
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DR EMBL; CBCY010000144; CDB05567.1; -; Genomic_DNA.
DR AlphaFoldDB; R6FU83; -.
DR STRING; 1262929.BN691_00356; -.
DR Proteomes; UP000018359; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd06308; PBP1_sensor_kinase-like; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 3.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR025997; SBP_2_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF13407; Peripla_BP_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Reference proteome {ECO:0000313|Proteomes:UP000018359};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 343..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 483..598
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 640..739
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT MOD_RES 531
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 742 AA; 83256 MW; E944B0708BBD3C1C CRC64;
MKTRISNTLF ILLATLVTLS GCTNHYKYKI GVSQCVGGAW RDKANVEMLS AQHLYDNDVK
VIIKNADNNN ERQCQQIDSL VDEGVDLLVV SPNDYHALNG SLQRAREKNI PIVFFDRTTA
LKDYTAYIGG DNVEAGRKMA EYAVLLCRDS VKTDGRRPIV LEMTGPLAIS PAAQRHAGFS
EVISKNPSID YRHVPSQWSY DDCKRIMREW LENGKAVDVV FCHSDLAAVG AYEAAKELHK
EREIRFLGID GLPGEGLDAV QNGQLAASYI YSTHGEEVIA LALRILEGKP FKRTNNLKSI
VVTPQNVADI ALSSHSLQKQ NTYLSTIQTK LETYLGFYHI QRALLIVSLL VILLLAVAVF
TTWRAVRATR RANRRMRELN DEQTRFFTNA SHQLRTPLTL IAGPVKQLAE GKGDRQQLVG
IVQRNVEQLQ RLVSDVLLFR RENSATVDDT TVATDEQLLA SRKAVQESRH DTLINDNAEE
LATVLIVDDN ADMRAYLRTL LLDRYYVIEA ADGQSGLKLA VESVPDIVVS DVMMPVMDGL
AFCTRLKQHE ATSHIPVLLL TARSSEQQCI EGLQTGADIY MTKPFSADLL LANIASLLAN
RQKLRQLFNT QNLNTQHLNT TPSQHLTTQN SPSPDRRFLD TFLKAMEKHM SNTNLKIEDL
GDEVGLSRVQ LYRKVKALTG MTPVEILRET RLKRAMQLLK TTDKTVSEIA NEVGFATPGY
FSSCFKKQYD KYPTDVREEM KV
//
