ID   R6G1Y4_9CLOT            Unreviewed;       496 AA.
AC   R6G1Y4;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=LPXTG-motif containing cell wall anchor domain protein {ECO:0000313|EMBL:CDB15494.1};
GN   ORFNames=BN542_00721 {ECO:0000313|EMBL:CDB15494.1};
OS   Clostridium sp. CAG:221.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262780 {ECO:0000313|EMBL:CDB15494.1, ECO:0000313|Proteomes:UP000018176};
RN   [1] {ECO:0000313|EMBL:CDB15494.1, ECO:0000313|Proteomes:UP000018176}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:221 {ECO:0000313|Proteomes:UP000018176};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB15494.1}.
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DR   EMBL; CBDC010000066; CDB15494.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6G1Y4; -.
DR   Proteomes; UP000018176; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR019931; LPXTG_anchor.
DR   InterPro; IPR041033; Prealbumin-like.
DR   NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR   Pfam; PF00746; Gram_pos_anchor; 1.
DR   Pfam; PF17802; SpaA; 1.
DR   SUPFAM; SSF49401; Bacterial adhesins; 1.
DR   SUPFAM; SSF49478; Cna protein B-type domain; 1.
PE   4: Predicted;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW   Secreted {ECO:0000256|ARBA:ARBA00022512};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        470..487
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          339..406
FT                   /note="Prealbumin-like fold"
FT                   /evidence="ECO:0000259|Pfam:PF17802"
FT   DOMAIN          455..494
FT                   /note="Gram-positive cocci surface proteins LPxTG"
FT                   /evidence="ECO:0000259|Pfam:PF00746"
FT   REGION          85..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          122..179
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        91..110
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        122..143
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        158..174
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   496 AA;  55010 MW;  E104DE76EA687E25 CRC64;
     MKGVKRRFAN VRNIALFISI FMFISLFSNI TVKADELENG EVNPVVSEQA ELQSNEEFDT
     ENELLIPEET TDYDDAQNDE VTSADLTGSG EELSEESKEE LPTAEEANKQ EEFFQEEILE
     EEIFEDEKEA EGAITEEEEE VIVPEETDKK PSDEPSEIEE PKDETNENEE PKEDEECNGQ
     MKISLLINGE EVNYEDNVSL NEDDDIDLRL KYNTIGKIKA GDTLEIKIPS FINVKDIEYE
     KMDFSEESIS DDGTVKLIFN ERILDVGQIY IGEITISGTI AHTEESVTEG TEVLVNGAAI
     IGASITAIPK VNTEPNPEEP AEEVYMGSVV LTNVERGNNE KVLDGSKFIL LDENLDKVGD
     IYTTNEQGQI TVDNLIEGDY YFVEIAPKAG YALDMIPVKF TISKDNEGPV LVFKENSLIP
     KLNFPNGNGN VSSGSTINKL SGLSMASKLS TNTSTNYRRT LPNTGGNSKA VELVVALAAI
     LIGFIFVRKN KKNNVT
//