ID R6G3B8_9CLOT Unreviewed; 689 AA.
AC R6G3B8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Transcriptional regulatory protein {ECO:0000313|EMBL:CDB15851.1};
GN ORFNames=BN542_01055 {ECO:0000313|EMBL:CDB15851.1};
OS Clostridium sp. CAG:221.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262780 {ECO:0000313|EMBL:CDB15851.1, ECO:0000313|Proteomes:UP000018176};
RN [1] {ECO:0000313|EMBL:CDB15851.1, ECO:0000313|Proteomes:UP000018176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:221 {ECO:0000313|Proteomes:UP000018176};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB15851.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CBDC010000079; CDB15851.1; -; Genomic_DNA.
DR AlphaFoldDB; R6G3B8; -.
DR Proteomes; UP000018176; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR003313; AraC-bd.
DR InterPro; IPR049166; GH39_cat.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR037923; HTH-like.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR PANTHER; PTHR43280; ARAC-FAMILY TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR43280:SF2; BIFUNCTIONAL TRANSCRIPTIONAL ACTIVATOR_DNA REPAIR ENZYME ADAA; 1.
DR Pfam; PF02311; AraC_binding; 1.
DR Pfam; PF01229; Glyco_hydro_39; 1.
DR Pfam; PF12833; HTH_18; 1.
DR PRINTS; PR00032; HTHARAC.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF51215; Regulatory protein AraC; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 175..273
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
SQ SEQUENCE 689 AA; 81382 MW; A3F8E437B75F226F CRC64;
MRKQYINYPS NLPVNISYYN IHNYPTHWHN STEIIYVLEG SINISIDTDS FTLKENEVEI
INPDECHSFS SENDNKVLIF QIDPDFFEKY YKDIRNVFFY TNSNDEEDQN GEKYDELKSL
LCKILCEFVQ TLEDFDEQIE DILINLLYHL INNFHYLTTD KEELKEKSEQ LDRYHRISKY
IFNNYNNNIT LQEIAKKEFL SPHYLSHEIK YATGHSFTDL INLTRIEESI KLLLDTTMSI
TEISEKIGFS HVRYYNKNFK SYFGCTPLQY RKKYYLNEND FDKSKNVTSL DLNGALNLLS
YNLENYDRFN FENKLWNIHI NMDESLNIFD NNFKDILNLG EAFDLLIEDN KDILEEVQEE
IHFTYGRLEK MFHNDMGVFI DSDFYNWNRA KAVLEFLYDI DIKPLIVIDN TAFTTEKYTN
VLKSFIEYFS ALDFSPIEDL KFQFSSTISK EIKNYLLDFL NNEFSFEVLQ DDFVIENTLN
QIYDTSYMLP YIIHNTIFKK DNLSFLRNFD VLEKATNITN EVFIGAPGIV NDMGIRKPSY
YAFYLLSKLA NEIVSIDDGC IVTKSDDLYA ILLYCHNNDM DSLAKYESIY KNGILKKSFK
KKYSLNIANL KSATRIITYT IDESTGSSYN YWLSMGSPKR LNKEEKEILH KASYPKIEFK
YSIKNSVLNI ITELNGYGAK LIILRNIKQ
//
