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Database: UniProt
Entry: R6GXR6_9FIRM
LinkDB: R6GXR6_9FIRM
Original site: R6GXR6_9FIRM 
ID   R6GXR6_9FIRM            Unreviewed;       833 AA.
AC   R6GXR6;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   10-APR-2019, entry version 23.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=BN557_00148 {ECO:0000313|EMBL:CDB25996.1};
OS   Oscillibacter sp. CAG:241.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Oscillospiraceae;
OC   Oscillibacter; environmental samples.
OX   NCBI_TaxID=1262911 {ECO:0000313|EMBL:CDB25996.1, ECO:0000313|Proteomes:UP000018113};
RN   [1] {ECO:0000313|EMBL:CDB25996.1, ECO:0000313|Proteomes:UP000018113}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:241 {ECO:0000313|Proteomes:UP000018113};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA   Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA   Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA   Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA   Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA   Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA   Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA   Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA   MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA   Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units
RT   of genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CDB25996.1}.
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DR   EMBL; CBDI010000041; CDB25996.1; -; Genomic_DNA.
DR   Proteomes; UP000018113; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018113};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018113};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    284    305       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    513    536       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    548    572       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    578    598       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    641    661       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    673    689       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    701    722       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    734    758       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    770    789       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    801    820       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        4    165       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
FT   COILED      224    244       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   833 AA;  91107 MW;  A0B3B930B16B8782 CRC64;
     MEKQIKIALA GNPNCGKTTL FNALTGSNQF VGNWPGVTVE KKEGKLKKHD DVVIMDLPGI
     YSLSPYTLEE VVARNYLIEE RPDAILNIID GTNLERNLYL TTQLTELGIP VVIAVNMMDV
     VRKNGDQINV KELSRQLGCE IVEISALKGD GVMEAAEAAV KAAQGKTKTI PMHTFSGPVE
     HAIAHIEEAA VHTMPEEQQR WYAIKIFERD DKVLQKMNIP ADVMQHIQQD IQAAEKELDD
     DAESIITNER YVYIAEIIKS CYKQKNKGQL STSDKIDKVV TNRWLGLPIF AVVMFLVYWI
     AMVAVGAPAT DWANDGVFDD GWHLLGIGSK AYNETNDEYT AAVQAVDAFL GTEIDPEAED
     FDAQTLLSDM KSFRPTSDTA TVDVEDEETL AINTMTAYYD TLPQGADKRD DVVQMTYVDA
     VKYLTENGFD APDPADYGVW VPGIPVLVSN GLESAGAADW LSGLINDGIV AGVGAVLGFV
     PQMLVLFLML AFLEACGYMA RIAFVLDRVF RKFGLSGKSF IPMLIGVGCG VPGVMASRTI
     ENERDRRMTV MTTTFIPCGA KVPFIAMIAG AIFGGSAWVS TSAYFIGMAA IIVSGIMLKK
     TKMFAGDPAP FVMELPAYHW PTLGNVLRSM WERGWSFIKK AGTIILLSTI FVWFTTYFGW
     VDGTFRMLDE SEIQSSILAA IGGVIAWIFK PLGWGNWQAA VASITGLVAK ENIVGTLGIL
     YGGGDGTVYQ NIGAAFTGIS GFSFLVFNLL CAPCFAAIGA IKREMNNRKW TWFAIGYQCG
     FAYLVGLMIN QFGNVFTGNL NVIGLIAALA ALALIVYMLV RPYKEATRLN AKV
//
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