ID R6GY66_9FIRM Unreviewed; 518 AA.
AC R6GY66;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=DHH subfamily 1 protein {ECO:0000313|EMBL:CDB29425.1};
GN ORFNames=BN490_00685 {ECO:0000313|EMBL:CDB29425.1};
OS Firmicutes bacterium CAG:137.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263004 {ECO:0000313|EMBL:CDB29425.1, ECO:0000313|Proteomes:UP000018011};
RN [1] {ECO:0000313|EMBL:CDB29425.1, ECO:0000313|Proteomes:UP000018011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:137 {ECO:0000313|Proteomes:UP000018011};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB29425.1}.
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DR EMBL; CBDK010000073; CDB29425.1; -; Genomic_DNA.
DR AlphaFoldDB; R6GY66; -.
DR Proteomes; UP000018011; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 3.10.310.30; -; 1.
DR Gene3D; 3.90.1640.10; inorganic pyrophosphatase (n-terminal core); 1.
DR InterPro; IPR001667; DDH_dom.
DR InterPro; IPR038763; DHH_sf.
DR InterPro; IPR003156; DHHA1_dom.
DR InterPro; IPR000160; GGDEF_dom.
DR PANTHER; PTHR47618; BIFUNCTIONAL OLIGORIBONUCLEASE AND PAP PHOSPHATASE NRNA; 1.
DR PANTHER; PTHR47618:SF2; CYCLIC-DI-AMP PHOSPHODIESTERASE GDPP; 1.
DR Pfam; PF01368; DHH; 1.
DR Pfam; PF02272; DHHA1; 1.
DR SUPFAM; SSF64182; DHH phosphoesterases; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000018011};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 44..172
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 518 AA; 56888 MW; 6796BAED8BBC13FA CRC64;
MKDRRYRVYG TTFHAGDSGG MLLGTVYLAD LTELYQVRDE YIRSRPVVAI ILVDNYDELT
KNLPEGAIST LNAELNEVIT RCTEGYHGLL RRLERNRFLF VFEVRDLKVS IENKFHLLEE
IRQVVSPTGV AATISLGIGR DGVSFEESYN FAALSIEMAL SRGGDQAVIK DRYNFSFYGG
RTKETDHRSK VRSRVTANSL SELIAQSSQV FVMGHKNADL DALGAAVGIC CLCRKKGKQA
KIVLDMERNA AGKLLERLNA VPEYANAFVS GQDALLQADP KSLLVVVDTN RPDQVECKPL
LDAISKVCVV DHHRRAADYI NPVVVNLHEP YASSASELVT ELLQYAVESS EVLQVEAMAL
LAGIVLDTKN FNVRTGERTF EAAAFLRRLG ADTVEVKKLL QNDFQATLAR YQIIKAARLY
REQIAIAALN GSTSRTIAAQ AADELLSIQG ILTSFVLYPC EGQVIISARS IGEANVQVIL
EPLGGGGNAA TAGAQLRDCD VKTALDRLVA SIDQYYDA
//
