ID   R6HCC0_9FIRM            Unreviewed;       725 AA.
AC   R6HCC0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Anaerobic ribonucleoside-triphosphate reductase {ECO:0000313|EMBL:CDB31196.1};
GN   ORFNames=BN490_02263 {ECO:0000313|EMBL:CDB31196.1};
OS   Firmicutes bacterium CAG:137.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1263004 {ECO:0000313|EMBL:CDB31196.1, ECO:0000313|Proteomes:UP000018011};
RN   [1] {ECO:0000313|EMBL:CDB31196.1, ECO:0000313|Proteomes:UP000018011}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:137 {ECO:0000313|Proteomes:UP000018011};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB31196.1}.
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DR   EMBL; CBDK010000582; CDB31196.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6HCC0; -.
DR   Proteomes; UP000018011; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   Gene3D; 3.20.70.20; -; 1.
DR   InterPro; IPR005144; ATP-cone_dom.
DR   InterPro; IPR012833; NrdD.
DR   NCBIfam; TIGR02487; NrdD; 1.
DR   PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   Pfam; PF03477; ATP-cone; 1.
DR   Pfam; PF13597; NRDD; 1.
DR   SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR   PROSITE; PS51161; ATP_CONE; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00492};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00492}; Reference proteome {ECO:0000313|Proteomes:UP000018011}.
FT   DOMAIN          1..94
FT                   /note="ATP-cone"
FT                   /evidence="ECO:0000259|PROSITE:PS51161"
SQ   SEQUENCE   725 AA;  82313 MW;  78BD1AC3F518B35A CRC64;
     MKIIKRNGAE AAFDISKIES AITRANAAVA EQFQMTATQI HRIAESVALS CQEMGRSPAV
     EEIQDLVEKA IMAHGAFEVA KQYITYRYTR SLIRKSNTTD DRILSLIESN NEEVKQENAN
     KNPTVNAVQR DYMAGEVSKD ITRRILLPKE IVEAHEAGII HFHDSDYYAQ HMHNCDLVNL
     EDMLQNGTVI SGTMIEKPHS FSTACNIATQ IIAQVASNQY GGQSISLTHL APFVQVSREK
     IRAAVERELR EFHVSPAPEI ISQVVEERLR EEIRRGVQTI QYQVVTLMTT NGQAPFITVF
     MYLNEAKSEQ EKKDLAVIIE EMLLQRCEGV KNETGVWITP AFPKLIYVLE EDNVREGTPY
     WYLTRLAAQC TAKRMVPDYI SEKKMLELKI DKNGEGHCYT CMGCRSFLTP YVDETGKPKY
     YGRFNQGVVT INLVDVALSS GKDQEKFWKI FDERLELCHQ ALMCRHNRLK GTLSDAAPIL
     WQYGALARLQ KGEPIDKLLY GGYSTISLGY AGLYECVKYM TGHSHTDAEA TPFALSVMQH
     MNDACAKWKK EHNIDFSLYG TPLESTTYKF AKCLQQRFGK IPGITDKSYI TNSYHVHVSE
     PIDAFTKLSF EAQFQRLSPG GAISYVEVPN MQSNIDAVLE VMQFIYENIM YAELNTKSDY
     CQVCGYDGEI EIQEDPDGKL VWTCPQCGNR DQSKMNVARR TCGYIGTQFW NQGRTQEIRD
     RVLHL
//