ID R6HI28_9ACTN Unreviewed; 384 AA.
AC R6HI28;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase {ECO:0000313|EMBL:CDB33639.1};
GN ORFNames=BN534_01375 {ECO:0000313|EMBL:CDB33639.1};
OS Eggerthella sp. CAG:209.
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Eggerthella.
OX NCBI_TaxID=1262875 {ECO:0000313|EMBL:CDB33639.1, ECO:0000313|Proteomes:UP000018042};
RN [1] {ECO:0000313|EMBL:CDB33639.1, ECO:0000313|Proteomes:UP000018042}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:209 {ECO:0000313|Proteomes:UP000018042};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; phospholipid metabolism.
CC {ECO:0000256|ARBA:ARBA00005074}.
CC -!- SIMILARITY: Belongs to the CDP-alcohol phosphatidyltransferase class-I
CC family. {ECO:0000256|ARBA:ARBA00010441, ECO:0000256|RuleBase:RU003750}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB33639.1}.
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DR EMBL; CBDM010000159; CDB33639.1; -; Genomic_DNA.
DR AlphaFoldDB; R6HI28; -.
DR UniPathway; UPA00085; -.
DR Proteomes; UP000018042; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008444; F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1760; -; 1.
DR Gene3D; 3.90.950.20; CinA-like; 1.
DR InterPro; IPR000462; CDP-OH_P_trans.
DR InterPro; IPR043130; CDP-OH_PTrfase_TM_dom.
DR InterPro; IPR048254; CDP_ALCOHOL_P_TRANSF_CS.
DR InterPro; IPR036653; CinA-like_C.
DR InterPro; IPR008136; CinA_C.
DR InterPro; IPR004570; Phosphatidylglycerol_P_synth.
DR NCBIfam; TIGR00560; pgsA; 1.
DR NCBIfam; TIGR00199; PncC_domain; 1.
DR PANTHER; PTHR13939; NICOTINAMIDE-NUCLEOTIDE AMIDOHYDROLASE PNCC; 1.
DR PANTHER; PTHR13939:SF0; NICOTINAMIDE-NUCLEOTIDE AMIDOHYDROLASE PNCC; 1.
DR Pfam; PF01066; CDP-OH_P_transf; 1.
DR Pfam; PF02464; CinA; 1.
DR SUPFAM; SSF142433; CinA-like; 1.
DR PROSITE; PS00379; CDP_ALCOHOL_P_TRANSF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018042};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003750};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 225..371
FT /note="CinA C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02464"
SQ SEQUENCE 384 AA; 40833 MW; 3DA73185EEA07C94 CRC64;
MTEKEFDETT LWTPANIVTL VRILLVPVFV VAIISPWPTY IPDWHNAELC KPWVAALIFA
ILSCTDALDG YLARSRGEVT NFGKFIDPLA DKILVAAALL ALIELQVLPS WVALLIIARE
FIVSGLRMLV ATHGVVVAAS WYGKFKTVFQ IIAILLFIVK GSDALLALHP DMELALYVIS
WFFMIVALAL TVVSMVDYFM KCAPILGFGN AGSKKDSDDF SCSPKAVIDR AIKEGKHLST
AESCTGGLIG GALTGVPGSS AVVEGGIISY SNDVKINVLG VSAADLERVG AVSSEVAASM
AEGSLRVANS DIAVAVTGIA GPGGAVPGKP VGTVWFGLAT KNHTKTFIRH FDGNRNAVRS
ATVDFALELF AYALDDSRSE PVSD
//
