ID R6HT78_9FIRM Unreviewed; 318 AA.
AC R6HT78;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Aminoglycoside phosphotransferase {ECO:0000313|EMBL:CDB41053.1};
GN ORFNames=BN517_01159 {ECO:0000313|EMBL:CDB41053.1};
OS Ruminococcus sp. CAG:177.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1262952 {ECO:0000313|EMBL:CDB41053.1, ECO:0000313|Proteomes:UP000018315};
RN [1] {ECO:0000313|EMBL:CDB41053.1, ECO:0000313|Proteomes:UP000018315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:177 {ECO:0000313|Proteomes:UP000018315};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB41053.1}.
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DR EMBL; CBDQ010000006; CDB41053.1; -; Genomic_DNA.
DR AlphaFoldDB; R6HT78; -.
DR STRING; 1262952.BN517_01159; -.
DR Proteomes; UP000018315; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR Pfam; PF01636; APH; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000018315};
KW Transferase {ECO:0000313|EMBL:CDB41053.1}.
FT DOMAIN 56..251
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
FT BINDING 60
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 318 AA; 35132 MW; A22B895DF786E3E1 CRC64;
MNVGRVIPKS LEPEKAAEYA LAVCEEGLGK SGVKTKNLGG GSFGTAVGVT FGDGSEAVVK
FLRADGMLEK ETHDLCLLSE NCGVRMPKVL YSRGADGSIP LDCYVMDKIE GSTLFMSFGK
LLYSKSAKLA FADKVTDALH GIHECRCDKF GDTMNPQFSS WLECYEPFME DVYLAAKQLS
EDGQLSPEIV SAMSRARDKF QNIFSQPVYD ACLIHGDLNV GNIMVGKGLR ITGFIDPLNS
MYADREYDLF QFNNLTGKRF FLCDTYLKKY GASEKAEQKL AFYALWNEVY CFVKAGTLIP
FIMNPLVKNM NAVLGRGV
//
