ID R6I6Q6_9FIRM Unreviewed; 247 AA.
AC R6I6Q6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=TVP38/TMEM64 family membrane protein {ECO:0000256|RuleBase:RU366058};
GN ORFNames=BN517_01177 {ECO:0000313|EMBL:CDB41071.1};
OS Ruminococcus sp. CAG:177.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1262952 {ECO:0000313|EMBL:CDB41071.1, ECO:0000313|Proteomes:UP000018315};
RN [1] {ECO:0000313|EMBL:CDB41071.1, ECO:0000313|Proteomes:UP000018315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:177 {ECO:0000313|Proteomes:UP000018315};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU366058};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU366058}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TVP38/TMEM64 family.
CC {ECO:0000256|ARBA:ARBA00008640, ECO:0000256|RuleBase:RU366058}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB41071.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CBDQ010000007; CDB41071.1; -; Genomic_DNA.
DR AlphaFoldDB; R6I6Q6; -.
DR STRING; 1262952.BN517_01177; -.
DR Proteomes; UP000018315; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR015414; TMEM64.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR12677:SF59; TVP38_TMEM64 FAMILY INNER MEMBRANE PROTEIN YDJZ; 1.
DR PANTHER; PTHR12677; UNCHARACTERIZED; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU366058};
KW Membrane {ECO:0000256|RuleBase:RU366058};
KW Reference proteome {ECO:0000313|Proteomes:UP000018315};
KW Transmembrane {ECO:0000256|RuleBase:RU366058};
KW Transmembrane helix {ECO:0000256|RuleBase:RU366058}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 64..91
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 97..116
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 176..197
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 209..234
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT DOMAIN 84..199
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
SQ SEQUENCE 247 AA; 27627 MW; EABC13D22270F944 CRC64;
MKKHWTRSGI MNAAGFALLI SAAAVSVVVY LLRYDQLWLW YKVYQEKLLE AEQFIQSLGI
SWKFVLAMLI VFLVRTFIPF LSVSAICVLT GAVLPSYWAL IVNFLGIIIM MSIKYFEGMK
FGSGNAWKII SKNERARKII ESSGKVNKAL LFALRLIPGF PLGSVSRIYG SLRFPYWQFI
LLSAAGFAPK LLSYTFMGTN VFDPLSSAFL VPLVIALTIS GASLLCVNLI WLLVEKSVSS
SKKNKDN
//
