ID R6I8Z2_9FIRM Unreviewed; 255 AA.
AC R6I8Z2; A0A6I3S3R2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Hydrolase carbon-nitrogen family {ECO:0000313|EMBL:CDB46653.1};
GN ORFNames=BN533_01709 {ECO:0000313|EMBL:CDB46653.1}, GMD11_03995
GN {ECO:0000313|EMBL:MTT75434.1};
OS Phascolarctobacterium faecium.
OC Bacteria; Bacillota; Negativicutes; Acidaminococcales; Acidaminococcaceae;
OC Phascolarctobacterium.
OX NCBI_TaxID=33025 {ECO:0000313|EMBL:CDB46653.1, ECO:0000313|Proteomes:UP000014944};
RN [1] {ECO:0000313|EMBL:CDB46653.1, ECO:0000313|Proteomes:UP000014944}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:207 {ECO:0000313|Proteomes:UP000014944};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MTT75434.1, ECO:0000313|Proteomes:UP000484547}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BIOML-A13 {ECO:0000313|EMBL:MTT75434.1,
RC ECO:0000313|Proteomes:UP000484547};
RX PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA Xavier R.J., Alm E.J.;
RT "A library of human gut bacterial isolates paired with longitudinal
RT multiomics data enables mechanistic microbiome research.";
RL Nat. Med. 25:1442-1452(2019).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB46653.1}.
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DR EMBL; CBDS010000087; CDB46653.1; -; Genomic_DNA.
DR EMBL; WNBM01000001; MTT75434.1; -; Genomic_DNA.
DR AlphaFoldDB; R6I8Z2; -.
DR STRING; 1262914.BN533_01709; -.
DR eggNOG; COG0388; Bacteria.
DR HOGENOM; CLU_030130_3_8_9; -.
DR OrthoDB; 9811121at2; -.
DR Proteomes; UP000014944; Unassembled WGS sequence.
DR Proteomes; UP000484547; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR CDD; cd07197; nitrilase; 1.
DR Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1.
DR InterPro; IPR003010; C-N_Hydrolase.
DR InterPro; IPR036526; C-N_Hydrolase_sf.
DR PANTHER; PTHR23088:SF27; DEAMINATED GLUTATHIONE AMIDASE; 1.
DR PANTHER; PTHR23088; NITRILASE-RELATED; 1.
DR Pfam; PF00795; CN_hydrolase; 1.
DR SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1.
DR PROSITE; PS50263; CN_HYDROLASE; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CDB46653.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000014944}.
FT DOMAIN 1..255
FT /note="CN hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS50263"
SQ SEQUENCE 255 AA; 27846 MW; B4E8CD5BFEFE134D CRC64;
MKIALCHLEI SRGPEHKNIE LLENAVRIAA DNGAKWVVTP ETAVQGYYFY KLNPDAKVDK
QPSVKLSHLL ALVKAYGLFL FLGCGEYDDG LKCNFNSCII FGPKGNICGT HRKLISHGSG
AEAWASRADV LEPVDCGNVK VGALVCADAW YSEHAQKMQQ KGAQIIIDIA AWPPTAVCGN
PLGAWEKCSE VTGLPMLVCN QTGVTEWMDM TVGQSVVIEN GKTKLSYNGK QAILLFEWDE
NSGKILSDKF EIISI
//
