ID R6I972_9FIRM Unreviewed; 780 AA.
AC R6I972;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Clp protease ATP-binding subunit ClpC {ECO:0000313|EMBL:CDB42999.1};
GN ORFNames=BN556_00537 {ECO:0000313|EMBL:CDB42999.1};
OS Firmicutes bacterium CAG:240.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263013 {ECO:0000313|EMBL:CDB42999.1, ECO:0000313|Proteomes:UP000018051};
RN [1] {ECO:0000313|EMBL:CDB42999.1, ECO:0000313|Proteomes:UP000018051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:240 {ECO:0000313|Proteomes:UP000018051};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB42999.1}.
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DR EMBL; CBDR010000017; CDB42999.1; -; Genomic_DNA.
DR AlphaFoldDB; R6I972; -.
DR Proteomes; UP000018051; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:CDB42999.1};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:CDB42999.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000313|EMBL:CDB42999.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018051}.
FT DOMAIN 174..318
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 516..688
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 687..776
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT REGION 101..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 386..446
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 103..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 780 AA; 87050 MW; 8852FF506B56DCC8 CRC64;
MQAKMCSRCG KNVAVVFITK LEGGVQKNEG LCLKCARELH IKPVDDMIEK MGISDEDLDN
LSGEMMNALN GVESLMDMSI DPDNDANDDS DDDGKTATFP FLNRLFGNGN NTPAESNNAA
AQQPPKEGGK PPKRKFLDNY CINLTDRARA GKLDNMVGRE EELERVIQIL NRRQKNNPCL
IGEPGVGKTA VAEGLAQRIA LDQVPYKLRG KEVYLLDLTA LVAGTQFRGQ FESRMKGLIE
EIRKQGNIIL VIDEVHNIVG AGDAEGSMNA ANILKPALSR GEIQVIGATT FTEYRKHIEK
DSALERRFQP VTINEPSVAD SIEILKGIRR YYEDYHGVKI SDEMCAEAVK MSERYITDRF
LPDKAIDLID EACSDVNLKD KNIVRRAELR KDLDDLKFER ETLMSADAPK GEELTDEALD
KRYERIAELR SKEMQREQEL ASLELEGVPE LTIDNLARII ELWTKIPASS IRKDEFERLA
ELDKRLKAHI VGQDEAVNAV CAAIKRSRVG LKAKRKPTSF IFVGGTGVGK TELVKRLAAD
LFDSPESLIR LDMSEFMEKF SVSRIIGSPP GYVGYDEAGQ LTEKIRRKPY SVVLFDEIEK
AHPDVLNILL QILDDGRITD AQGRTVNFEN TVIVMTTNAG SNRKGGAMGF GGTVNDMGRE
RALKALGEFL RPEFINRVDE IVYFNSLTEE NFRSIAKLML EETRDAIAER GISMTWNTAL
IDYLVRKSYS VTYGARNLRR TIQKDVEDAI AQKIIDCRGE NAGHISVSAD DNGVIVEVGE
//
