ID   R6K6D7_9FIRM            Unreviewed;       231 AA.
AC   R6K6D7;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=Thiamine phosphate synthase/TenI domain-containing protein {ECO:0000259|Pfam:PF02581};
GN   ORFNames=BN564_00462 {ECO:0000313|EMBL:CDB69005.1};
OS   Eubacterium sp. CAG:252.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=1262887 {ECO:0000313|EMBL:CDB69005.1, ECO:0000313|Proteomes:UP000017970};
RN   [1] {ECO:0000313|EMBL:CDB69005.1, ECO:0000313|Proteomes:UP000017970}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:252 {ECO:0000313|Proteomes:UP000017970};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Cofactor biosynthesis; thiamine diphosphate biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004948}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB69005.1}.
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DR   EMBL; CBEA010000151; CDB69005.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6K6D7; -.
DR   Proteomes; UP000017970; Unassembled WGS sequence.
DR   GO; GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd00564; TMP_TenI; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR036206; ThiamineP_synth_sf.
DR   InterPro; IPR022998; ThiamineP_synth_TenI.
DR   PANTHER; PTHR20857:SF15; THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME; 1.
DR   PANTHER; PTHR20857; THIAMINE-PHOSPHATE PYROPHOSPHORYLASE; 1.
DR   Pfam; PF02581; TMP-TENI; 2.
DR   SUPFAM; SSF51391; Thiamin phosphate synthase; 1.
PE   4: Predicted;
KW   Thiamine biosynthesis {ECO:0000256|ARBA:ARBA00022977}.
FT   DOMAIN          6..83
FT                   /note="Thiamine phosphate synthase/TenI"
FT                   /evidence="ECO:0000259|Pfam:PF02581"
FT   DOMAIN          140..227
FT                   /note="Thiamine phosphate synthase/TenI"
FT                   /evidence="ECO:0000259|Pfam:PF02581"
SQ   SEQUENCE   231 AA;  25507 MW;  F971879C72C49C29 CRC64;
     MLNDVIAITN RKLCQRDFLE QIKRVCEAGP KAIILREKDL SQKEYTKLAE QVYNITNIYN
     VRLIIHTHIS VAEELGLDTV HMSLQHFREY KEYMDGIADA NNTSVTPDKS TDASTSSTPA
     RIDCSIYPAD EPEAVSHIVL HKKIGCSIHS VEEAVEAQKL GASYITAGHI YATDCKKGLA
     PRGLEFLKEV CDSVTIPVYA IGGIDVEGTR RDEVKMCGAA GSCIMSGMMR L
//