ID R6LFR7_9BACE Unreviewed; 777 AA.
AC R6LFR7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN ORFNames=BN506_00569 {ECO:0000313|EMBL:CDB73032.1};
OS Bacteroides cellulosilyticus CAG:158.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=1263038 {ECO:0000313|EMBL:CDB73032.1, ECO:0000313|Proteomes:UP000018191};
RN [1] {ECO:0000313|EMBL:CDB73032.1, ECO:0000313|Proteomes:UP000018191}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:158 {ECO:0000313|Proteomes:UP000018191};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB73032.1}.
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DR EMBL; CBEB010000390; CDB73032.1; -; Genomic_DNA.
DR AlphaFoldDB; R6LFR7; -.
DR Proteomes; UP000018191; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR30620:SF16; LYSOSOMAL BETA GLUCOSIDASE; 1.
DR PANTHER; PTHR30620; PERIPLASMIC BETA-GLUCOSIDASE-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000018191};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..777
FT /note="beta-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004412634"
FT DOMAIN 692..761
FT /note="Fibronectin type III-like"
FT /evidence="ECO:0000259|SMART:SM01217"
SQ SEQUENCE 777 AA; 86339 MW; A8C7C02EBEE1D6E7 CRC64;
MNRKLILSAA LSGLMLTATA QTTVAPAIPR DGKIEKKVEA LLKKMTLEEK IGQMTELTID
VITKRDNSTQ EFQIDDALLD TVIGKYKVGS ILNVPQGVAQ SKEKWEEIIR KIQDKSMKVM
GIPCIYGVDQ IHGTTYTLGG TFFPQGINMA ATFNRELVRE GARISAYETK AGSIPWTYAP
VLDLARDARW PRHWENYGED CYVNAEMGRE AVFGFQGSDP NHIGKQQVAA CIKHYMGYGV
PVSGKDRTPS SITVQDMREK HFAPFLEGIK AGALSVMVNS AMNNGLPFHA NYELLTEWLK
EDLNWDGMIV TDWADINNLY TRDKIAGSKK EAIKIAINAG IDMSMVPYEW SFCTYLKELV
EEGEVPMSRI DDAVRRVLRM KYRLGLFETP AYNHKDFPLF GGKEHAAAAL QAAEESLVLL
KNTDHILPLP KDKKLLITGP NANSMRTLNG GWSYTWQGHR ADELAADYNT ILESFTQKFG
ASNIIYEPGV TYKEGGAWWE ENAPEIDKAV AAAANADYII ACVGENSYCE TPGNLNNLFL
SESQLNLVKA LAATGKPVVL VLNEGRPRIV NEIEPLAKAV INTMLPGNYG GDALANLVAG
DANFSGKMPY TYPKEINSLF TYDYKPCEDL EKMSGAYDYD AVMSVQWAFG YGLSYTTYAY
SNLKADKNNF TADDVLTFTV DVKNTGNRIG KESVLLFSSD LIASLTPDIR RLRAFEKVEL
QPGETKTVTL KVKGSDLAFV GYDGKWILEK GDFRIQTGNQ TLNITCTDTR KWDTPNK
//
