ID R6ML10_9FIRM Unreviewed; 950 AA.
AC R6ML10;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Putative signaling protein {ECO:0000313|EMBL:CDB99375.1};
GN ORFNames=BN647_02365 {ECO:0000313|EMBL:CDB99375.1};
OS Firmicutes bacterium CAG:41.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263021 {ECO:0000313|EMBL:CDB99375.1, ECO:0000313|Proteomes:UP000018139};
RN [1] {ECO:0000313|EMBL:CDB99375.1, ECO:0000313|Proteomes:UP000018139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:41 {ECO:0000313|Proteomes:UP000018139};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB99375.1}.
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DR EMBL; CBEM010000178; CDB99375.1; -; Genomic_DNA.
DR AlphaFoldDB; R6ML10; -.
DR Proteomes; UP000018139; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 4.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00497; SBP_bac_3; 2.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00062; PBPb; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 2.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018139};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..950
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004426237"
FT TRANSMEM 503..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 557..687
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 696..950
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 950 AA; 108118 MW; F4DA2613C20C2C15 CRC64;
MKNIKAIILM LLTSVICFTS FSVYAETNTL KAGILNDYSF DGNSISEYAE DSVNTILDTT
ASTNFIANEI NFDDTTFNKG ISDLQSGNID FLCMVPMSDA FLAYVDYTSS PIATGFLGLY
TTDYKQLYFE EFDTFNQIKI GLLKNSYIEK ILSDFSAANN FTYIPVYYDT VDDMLNAVKN
NSIDAIFTPT TNNPDGLKLI AKGGKFDYYC AVKKGNTNLL TKLNSAINQY KIQNPFYLSM
EYTKLFKRPY SNSIGYTKEE QTAKENHPKL RILAPDNNYP SSYYDKDTGE YNGIYEDIIK
KVADNAGFEI EFISYDQSEM SMNGIVMGKA DIILTVSGSK QGLTTATLPY TKVSYLPLVK
KDTNIFEDSE IHVGILADDS WITDYLDDKY KQWSIEKYSS IDSLLTAVEN DTVSAVLVSS
TDLQTKTSLI AHPKLSILQD FDVEVPASIG VSNLTCNQHI VSLLNKTIQN VTLTNSELER
KVYTLNHIYV PTVKDMLKTN KQWIFIILLV IIAIIVFIKW REYYYKKLLH TDTLTQIPNK
QYFMKTAEKI LDNNSDKSYL LTSLDARNFK LINERFGHIV GDQTLMNIAK NIKSKFHKNG
LYARSQGDSF LILVEDTSQN RELLKSLVDL DISIHNTTNY KVPLKIGVCP IPRYNPALSL
SLYIDRANIA KKYTSARNTN YICYFTDDMN KKLNMKNMIE SEMVRALSKS EFVVYYQPKY
ELANDTIIGA EALVRWNHKE KGIISPGVFI PVFERNGFIV DLDFYVYEQV LKMQKHRLDM
GKKVIPISMN VSRCHLSDTN FVDKLEAVVA KYKVPKQYIE MEITESIFSQ EDSSAIALIY
NLKEHGFTIS MDDFGSGYSS LNLLRKVPID TLKIDKVFID STEDVQRSQV IVEEIINMAS
KIHVKTICEG VETQSQRDFL KNAGCNMVQG YFYSKPLPYE DFSDLLNSSK
//
