ID R6N974_9FIRM Unreviewed; 608 AA.
AC R6N974;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Glycerophosphodiester phosphodiesterase family protein {ECO:0000313|EMBL:CDC08553.1};
GN ORFNames=BN627_02133 {ECO:0000313|EMBL:CDC08553.1};
OS Lachnospiraceae bacterium CAG:364.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1262983 {ECO:0000313|EMBL:CDC08553.1, ECO:0000313|Proteomes:UP000017986};
RN [1] {ECO:0000313|EMBL:CDC08553.1, ECO:0000313|Proteomes:UP000017986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:364 {ECO:0000313|Proteomes:UP000017986};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC08553.1}.
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DR EMBL; CBER010000080; CDC08553.1; -; Genomic_DNA.
DR AlphaFoldDB; R6N974; -.
DR Proteomes; UP000017986; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd08579; GDPD_memb_like; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR018476; GlyceroP-diester-Pdiesterase_M.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR46211; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR PANTHER; PTHR46211:SF8; PHOSPHODIESTERASE-RELATED; 1.
DR Pfam; PF03009; GDPD; 1.
DR Pfam; PF10110; GPDPase_memb; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017986};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 357..588
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 608 AA; 70052 MW; A72719AD149F4920 CRC64;
MKKILKQTWK TIRYNIRSLL IFEAGYRAAT FFLVMQLVRF FVDFSLKQQG FSYLTAENYK
EFLQYPLSVV FLALVFLVIL IFYFVEVAAL LCGFVYSAKE KKLYAGDFFI LGIKKTVSFF
RHSKVSWLVC AACSGPFLAA YFLVREISYI QILEFTARQI YKEIKSPMLI YGFLGVLLLI
SFLFVFALPY CILEKKKNWQ GFLSGMKLFR THWKRILLDF CFLHVFMLLF ILITYSVVML
ILAAGVFFFK PEAVKISSIF IYSEYVNMAL GIYAGGVQLI GSIAFVYTVY TKFHIQPKDE
EEHLFYKKME QYFWYSKLGR RKAAGLLTAL FVLLEGIYFG FLVINHDTTL SHLAADTEIT
AHRGGAWKAP ENTISALQYT IDSGADYAEI DVQETKDGEL ILLHDDSLKR TAGVKKNVWD
MTLKQVEKLD AGASFHKNFR GEKIPEFTEV LKFCKGRLDL NIEIKYNGKN KGIVNKVVRA
IKENHFEDHC VVTSMNYQFL KQIKKTAPEI RTGYIMTMTY GGVQGMEAAG FFSVKHTYVD
EKFVTQAHAL GKEVHVWTVN YKGDAKRMLD MGVDNIITDD PIMVRKVQNR ESGSSTGYVE
LLRYAFRF
//
