ID   R6NB53_9FIRM            Unreviewed;       901 AA.
AC   R6NB53;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=4Fe-4S ferredoxin-type domain-containing protein {ECO:0000259|PROSITE:PS51379};
GN   ORFNames=BN627_02035 {ECO:0000313|EMBL:CDC08415.1};
OS   Lachnospiraceae bacterium CAG:364.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1262983 {ECO:0000313|EMBL:CDC08415.1, ECO:0000313|Proteomes:UP000017986};
RN   [1] {ECO:0000313|EMBL:CDC08415.1, ECO:0000313|Proteomes:UP000017986}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:364 {ECO:0000313|Proteomes:UP000017986};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
CC         Evidence={ECO:0000256|ARBA:ARBA00001917};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC08415.1}.
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DR   EMBL; CBER010000077; CDC08415.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6NB53; -.
DR   Proteomes; UP000017986; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   PANTHER; PTHR43073; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR   PANTHER; PTHR43073:SF2; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF00037; Fer4; 2.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 2.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 2.
DR   PROSITE; PS51379; 4FE4S_FER_2; 2.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017986}.
FT   DOMAIN          288..317
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
FT   DOMAIN          837..866
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   901 AA;  100472 MW;  8D977EF85523367E CRC64;
     MAEKRELILK LGQKITDRIG HKVTVDDPEY WGLACIVTDE MAEVALKMKV RKPMTFPQLL
     KATGKEEKEL EKLLEEMSIV GLLEYNWENP QKEKQYILPM FVPGSAEFTN MNRKQLEEHP
     ELGRFFERMS RLPLEKVTPM VPPGGAGIGM HVIPVEKAIE MENQSIDIEH ISHWLKKYEG
     KYAASPCSCR LSRQTYEEGC ADDPEDWCIA VGDMADYVVE TQKGGRYITY EEVLDILKKA
     EDNGFVHQIT NIDGKNKIFA ICNCNVNVCY ALRTSQLFNT PNMSRSAYVA HVKTENCVAC
     GRCVEYCPAG AVKLGQKLCT KDGPIEYPKH ELPDAMKWGP EKWDEDYRDN NRINCYDTGT
     APCKTACPAH IAVQGYLKKA AQGKYREALA LIKKENPFPA VCGHICNRRC EDACTRGTID
     QAVAIDEVKK FIAKQDLTAE NRYIPPIIPP TTGRLFEEKI AIIGGGPAGL SCAFYLAEKG
     YKPTVFEKNE KPGGMLVYGI PSFKLEKDVV EAEIDVMRQM GVEIKCGIEV GKDITLEELR
     KQGYKAFYLA IGCQGGRKAN IQGEDAEGVM TAVDFLRTVG DNQNYPVEGR AVVVGGGNVA
     IDVARTASRC GASEVSMFCL EGREIMPASE EEITEAQEEG ITLNCGWGPK EILTENGKVK
     GIVFKKCLSV FDENKRFAPK FDEAVTMTVP CERVFLSIGQ SIVWGNLLEG SKVELGRGNG
     AVADKVTYQT AEPDIFVGGD VYTGPKFAID AIAAGKEGAI SIHRFVQPHS SLTIGRNRRQ
     FIELDKSNIQ IEEYDNSSRQ IPGMRKDIDA HKSFRDAKEA FTEEQVKKET ARCLGCGASV
     VDENKCIGCG VCTTKCEFDA IHLYREHPEC STMHKSEDKM KVILPYAFKR EMKIRFGKKE
     K
//