ID   R6NM82_9CLOT            Unreviewed;       696 AA.
AC   R6NM82;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Glutamine synthetase {ECO:0000256|ARBA:ARBA00021364};
GN   ORFNames=BN649_00993 {ECO:0000313|EMBL:CDC13293.1};
OS   Clostridium sp. CAG:413.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262803 {ECO:0000313|EMBL:CDC13293.1, ECO:0000313|Proteomes:UP000018076};
RN   [1] {ECO:0000313|EMBL:CDC13293.1, ECO:0000313|Proteomes:UP000018076}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:413 {ECO:0000313|Proteomes:UP000018076};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC       {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC13293.1}.
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DR   EMBL; CBES010000190; CDC13293.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6NM82; -.
DR   STRING; 1262803.BN649_00993; -.
DR   Proteomes; UP000018076; Unassembled WGS sequence.
DR   GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR   GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.20.120.1560; -; 1.
DR   Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR   InterPro; IPR040577; Gln-synt_C.
DR   InterPro; IPR008147; Gln_synt_N.
DR   InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR   InterPro; IPR008146; Gln_synth_cat_dom.
DR   InterPro; IPR027303; Gln_synth_gly_rich_site.
DR   InterPro; IPR022147; GSIII_N.
DR   PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR   PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR   Pfam; PF00120; Gln-synt_C; 1.
DR   Pfam; PF18318; Gln-synt_C-ter; 1.
DR   Pfam; PF12437; GSIII_N; 1.
DR   SMART; SM01230; Gln-synt_C; 1.
DR   SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR   PROSITE; PS00181; GLNA_ATP; 1.
DR   PROSITE; PS51986; GS_BETA_GRASP; 1.
DR   PROSITE; PS51987; GS_CATALYTIC; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018076}.
FT   DOMAIN          62..151
FT                   /note="GS beta-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS51986"
FT   DOMAIN          156..585
FT                   /note="GS catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS51987"
SQ   SEQUENCE   696 AA;  77796 MW;  0C6A4C12F2CF8B92 CRC64;
     MRSVTDYFGC MVFDDKAMRL RLPPEIYEAM KKTIRDGKRL DIAVANAVAD AMKEWAVENG
     ATHYTHWFQP MTGITAEKHD SFVSPGKSGT AIMEFSGKEL VKGESDASSF PSGGLRATFE
     ARGYTAWDPT SYAFIKEGVL CIPTAFCSYG GEALDLKTPL LRSMEALSRQ AVRILKLFGQ
     EYESVKTTVG AEQEYFLIDK AMYDRRKDLR YTGRTLFGAK PPKGQELDDH YFGSIKPRVS
     AFMNELDEEL WKLGVFAKTE HNEVAPAQHE LAPVFAVTNI ATDHNQLTME IMQKVARKHG
     MVCLLHEKPF EGVNGSGKHN NWSISTTDGV NLLEPGETPY ENAQFLLFLC AVIKAVDDYQ
     DLLRISVASA GNDHRLGANE APPAIVSMFL GDELSDILEA IENETAYDAR EKAVMKVGVH
     ILPRFAKDTT DRNRTSPFAF TGNKFEFRML GSANSIASAN IVLNTVVAQS LKSYADRLES
     ADDFEEALHS LIRKTIKDHK RIIFNGNGYD NEWIAEAERR GLLNLPTTPD CLPYLLKDKN
     IKLFAEHKVF SRQEIEARYE IYLESYCKNV RIEALTMTDM TNKDILPAVS AYFKTLCDTV
     KTMGRAGIDP SGSYEQVTAE KLATLSRKIF SAVHGLSQAV DGLSEAGDAA RESELIRDRV
     LPQMNLLREY VDAAESITAE EYWPYPSYGD LLFGVQ
//