ID   R6NWA5_9FIRM            Unreviewed;       484 AA.
AC   R6NWA5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Mucin-desulfating sulfatase {ECO:0000313|EMBL:CDC10506.1};
GN   ORFNames=BN627_00670 {ECO:0000313|EMBL:CDC10506.1};
OS   Lachnospiraceae bacterium CAG:364.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1262983 {ECO:0000313|EMBL:CDC10506.1, ECO:0000313|Proteomes:UP000017986};
RN   [1] {ECO:0000313|EMBL:CDC10506.1, ECO:0000313|Proteomes:UP000017986}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:364 {ECO:0000313|Proteomes:UP000017986};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the sulfatase family.
CC       {ECO:0000256|ARBA:ARBA00008779}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC10506.1}.
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DR   EMBL; CBER010000139; CDC10506.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6NWA5; -.
DR   Proteomes; UP000017986; Unassembled WGS sequence.
DR   GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:UniProt.
DR   CDD; cd16149; sulfatase_like; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR024607; Sulfatase_CS.
DR   InterPro; IPR000917; Sulfatase_N.
DR   PANTHER; PTHR42693:SF33; ARYLSULFATASE; 1.
DR   PANTHER; PTHR42693; ARYLSULFATASE FAMILY MEMBER; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR   PROSITE; PS00523; SULFATASE_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017986}.
FT   DOMAIN          2..349
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
SQ   SEQUENCE   484 AA;  55800 MW;  B46FF84D99D61FCD CRC64;
     MNILFIMADD QGSWAMNCGG TKELCTPNLN RIAESGMQFQ NFYCVSPVCS PARASVLTGD
     IPSSHGVHDW IRSGNIDKDK FEEAGRENPY WNGYSCEDKP ISYLEGKTTY TDVLNENGYR
     CALAGKWHLG DSVCPQHGFS KWYTIGLGGC DYFHPDIVEN GNIKVLHEQY VTEVIANKAI
     EYLNEFQHQE EPFYLSVHFT APHSPWGEEQ HPKKWMDYYE NCDFQSIPDE ADHPDLTTGP
     VFGTEKRKEN LRGYFAAISA MDEQIGRILD TLEANGLREN TLVVYTADNG MSMGHHGVWG
     KGNGTFPFNM YETSVKVPFL MSLPGVIPQG KREETILSAY DIFPTLLELC KLDRKECEKL
     PGRSFAYLLR WEKEQKKRDE EIVVFDEYGP VRMIRNQDWK YIHRYPYGPH ELYYLTEDPE
     EKENLYGQPE YEKMVVEMRT RLNEWFNKYA DEKVDGVKES VTGLGQMCRA GIYSEKTDTY
     YCEK
//