ID   R6NWS0_9FIRM            Unreviewed;       899 AA.
AC   R6NWS0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=4Fe-4S ferredoxin-type domain-containing protein {ECO:0000259|PROSITE:PS51379};
GN   ORFNames=BN662_01718 {ECO:0000313|EMBL:CDC10716.1};
OS   Roseburia sp. CAG:45.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=1262947 {ECO:0000313|EMBL:CDC10716.1, ECO:0000313|Proteomes:UP000018173};
RN   [1] {ECO:0000313|EMBL:CDC10716.1, ECO:0000313|Proteomes:UP000018173}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:45 {ECO:0000313|Proteomes:UP000018173};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC10716.1}.
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DR   EMBL; CBET010000037; CDC10716.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6NWS0; -.
DR   Proteomes; UP000018173; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.30.70.20; -; 2.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   PANTHER; PTHR43100:SF2; FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE, CHLOROPLASTIC-LIKE; 1.
DR   PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   Pfam; PF00037; Fer4; 2.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 2.
DR   PROSITE; PS51379; 4FE4S_FER_2; 2.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018173}.
FT   DOMAIN          286..315
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
FT   DOMAIN          835..864
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   899 AA;  99377 MW;  397E4F9EF9304BD6 CRC64;
     MAEPRELILK LGQKITDRIG VKVTENDPEY WGLASVVTDE MAEVALAMKV RVPATAAEVA
     KKCKKSVERT EELLEKMSVI GVIEYNWENE DHHKQYVLPM FVPGCAEFMV MNKEQVEEHT
     EIADFFEQMA RLPLEKVTPM VPLGGAGIGM HVIPVEKAIP ANQQSASVEH ISHWLNKYDK
     YSVGACSCRR QQRIRGEGTG DLEDDLCIGV GDMADYCVET GKGRYIDYDE VMEILQRAED
     NGYVHQITNI DGEDKIFAIC NCAVGVCNAL RTSQLFNTPN MSRSAYRASV EPEKCVACGR
     CVEYCPAGAA KLGQKLCTKD GGHITYPQQE LPDTTKWGPE KWNPNYRDDN QINCYDTGTA
     PCKTACPAHL PVQGYIKMAS QGRYLDALKL IKTENPFPAV CGAICNRRCE DACTRGTIDQ
     AVAIDEIKKF IAEQELHAEK RYIPPMLNYS GKPFEEKVAV IGAGPAGMSA AFYLKKMGYP
     VTVFEKEKRP GGMLMNGIPS FRLEKDVINA EIDVLREMGV EFKCGVEVGE DITIAQLREQ
     GYKAFYIAIG AQGGRMTGVP GEDAVGVETG VDFLRRVNLN EEGVKLSGKT VVIGGGNVAV
     DVARTALRTG SSDVSMFCLE SRDIMPAADD EVAEAEEEGI VVNNSWGPKE ILTENGKVTA
     VVFKKCISVL DENKRFSPKY DEEELLTVPC DQVLLSIGQS IKWGALLEGT RVEFNPNGTL
     KADPVTYQTA EPDIFTGGDN YTGPRFAIDA IAAGKEGCVS IHRFVHEGQS LTLGRNRRQF
     IELDKDNIKV ETFDNAKRQV PGHKAGDAKH TFRDLRSTFT EEQVQKEANR CLGCGATVVD
     PNKCIGCGIC TTKCEFDAIH LSRDLPDASR MVKSEDKLKA IFPYMLKREI KIKFKGRKK
//