ID R6PGC5_9CLOT Unreviewed; 771 AA.
AC R6PGC5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=H+-symporter {ECO:0000313|EMBL:CDC08822.1};
GN ORFNames=BN649_01165 {ECO:0000313|EMBL:CDC08822.1};
OS Clostridium sp. CAG:413.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262803 {ECO:0000313|EMBL:CDC08822.1, ECO:0000313|Proteomes:UP000018076};
RN [1] {ECO:0000313|EMBL:CDC08822.1, ECO:0000313|Proteomes:UP000018076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:413 {ECO:0000313|Proteomes:UP000018076};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC family. {ECO:0000256|ARBA:ARBA00009617}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC08822.1}.
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DR EMBL; CBES010000026; CDC08822.1; -; Genomic_DNA.
DR AlphaFoldDB; R6PGC5; -.
DR STRING; 1262803.BN649_01165; -.
DR Proteomes; UP000018076; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR InterPro; IPR039672; MFS_2.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11328:SF24; INNER MEMBRANE SYMPORTER YICJ-RELATED; 1.
DR PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13347; MFS_2; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018076};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022847}.
FT TRANSMEM 32..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT COILED 734..768
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 771 AA; 86903 MW; B2DE6FAEE6C933F8 CRC64;
MEFLDKAKNL LSDAKVYWRT PLKGRYMPFK EIAAYSFGGI GVYCIIYMSY TMIISGTNVV
MTNLTGIPPK YLLIIYYICT IAGIPFTALR AHMIDNMRLK AGKYRPWILG MGIPSVVIML
AMLFTPYQSM SKAAAYIITT VYSLALNFVY NFFYEAYENL VFLLSPNTQE RADVSSVKSI
TYSLAPTVLN PLLPLMSKLL NTGDMYDVRI YKVMFPIISV IGIALSIVVF ANTKEKIIQA
KTHVIQIGFF EAIKAVAKNK YFWIISLAGW IGFLENSQSY ILGWLYNYGK LCTDGQYSLI
TIIYGNASLW GMLAAPFAIR RWGKKAVLVV TNLFNILFIA LMFPSVGIRS IWLVLVCLWM
NALMGSFAHI LTPAINADIR DYQQYMTGER IDGMFSAISL ITSFITMATS TVIPLIFDRF
GINEHNKYAN AYDILKYQPD TLYSLIHLLI LLSVIGATLN VLPYFFYDLS ETKQRAMVNI
LKIRAMFEDF GNDALKDREL IEGVDVLHAA MADSGKEPVA VDSSFNRKER RAAREANENI
TIAKMVMAEY DKFSGEEFTF KLAHARKTVA AGVDGILEAD KSMIAEAKAM PSATPDEKAI
RKYCIEFAKQ SLRSKKIVVK HYNGTMPEFN ADIFETLFEE ENKNDEAKQA AYAKLDAAKA
SKDSAQIAAT KNEIKALTNE GYVIRGKIKQ ATRDNTKYNH AIKPYADAQK LIKQSENYGR
FVEIEELYEA ATERVATEDA AAKAQAEKEA LERKLDKERR IAEKKAAKSR K
//
