ID R6PL07_9FIRM Unreviewed; 473 AA.
AC R6PL07;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Iron-only hydrogenase maturation rSAM protein HydG {ECO:0000313|EMBL:CDC21509.1};
GN ORFNames=BN582_01450 {ECO:0000313|EMBL:CDC21509.1};
OS Eubacterium sp. CAG:274.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1262888 {ECO:0000313|EMBL:CDC21509.1, ECO:0000313|Proteomes:UP000017904};
RN [1] {ECO:0000313|EMBL:CDC21509.1, ECO:0000313|Proteomes:UP000017904}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:274 {ECO:0000313|Proteomes:UP000017904};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC21509.1}.
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DR EMBL; CBEX010000101; CDC21509.1; -; Genomic_DNA.
DR AlphaFoldDB; R6PL07; -.
DR STRING; 1262888.BN582_01450; -.
DR Proteomes; UP000017904; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0044271; P:cellular nitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0018130; P:heterocycle biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR GO; GO:0042364; P:water-soluble vitamin biosynthetic process; IEA:UniProt.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR010722; BATS_dom.
DR InterPro; IPR024007; FeFe-hyd_mat_HydG.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR034428; ThiH/NoCL/HydG-like.
DR NCBIfam; TIGR03955; rSAM_HydG; 1.
DR PANTHER; PTHR43583; 2-IMINOACETATE SYNTHASE; 1.
DR PANTHER; PTHR43583:SF2; BIOTIN AND THIAMIN SYNTHESIS ASSOCIATED DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF06968; BATS; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDF00319; Fe_hydrogenase_maturase_(HydG; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00876; BATS; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000017904};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 275..384
FT /note="Biotin and thiamin synthesis-associated"
FT /evidence="ECO:0000259|SMART:SM00876"
SQ SEQUENCE 473 AA; 53547 MW; 3F0048D82B2B7C41 CRC64;
MYNPKSLKAE EFISHEEIQE TLAFADANKN NVELIDSIIE KAKLKKGLTH REASVLLACE
IPEKNEEVFA LAKKIKDDFY GNRIVMFAPL YLSNYCVNGC VYCPYHAKNK HIARKKLTQE
EVKREVIALQ DMGHKRLAIE AGEDPVNNPI DYILDCIKTI YSIKHKNGAI RRVNVNIAAT
TVENYRKLKD AGIGTYILFQ ETYHKESYEK LHPTGPKHNY AYHTEAMDRA MEGGIDDVGC
GVLFGLEKYR YEFAGLLMHA EHLEAVHGVG PHTISVPRIR RADDIDPDAF SDGIDDNIFA
KIVACIRVAV PYTGMIISTR ESKACREKVL QLGVSQISGG SRTSVGGYVE PEEPDDLTSE
QFDVEDKRSL DEVVHWLMDL GFIPSFCTAC YREGRTGDRF MSLCKNEQIH NCCLPNALMT
LKEYLMDYAA EDTKIAGEKV IAKELEHIPN EKVRGIVIER LKEIADGQRD FRF
//
