ID   R6QP30_9FIRM            Unreviewed;       442 AA.
AC   R6QP30;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN   ORFNames=BN563_00727 {ECO:0000313|EMBL:CDC32621.1};
OS   Eubacterium sp. CAG:251.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=1262886 {ECO:0000313|EMBL:CDC32621.1, ECO:0000313|Proteomes:UP000018414};
RN   [1] {ECO:0000313|EMBL:CDC32621.1, ECO:0000313|Proteomes:UP000018414}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:251 {ECO:0000313|Proteomes:UP000018414};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC32621.1}.
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DR   EMBL; CBFD010000028; CDC32621.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6QP30; -.
DR   STRING; 1262886.BN563_00727; -.
DR   ESTHER; 9firm-r6qp30; Carb_B_Bacteria.
DR   Proteomes; UP000018414; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR   PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR   Pfam; PF00135; COesterase; 2.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018414}.
FT   DOMAIN          5..324
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
FT   DOMAIN          334..421
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   442 AA;  49669 MW;  FEFBF37123916517 CRC64;
     MKTVELQTKC GKIQGIDGEN CLEFRGIKYA NAKRWEYPQV IEKWQGVFDA TCFKECSYQH
     RGFDDDATVN PFYHYEFRDG LAFTYSEDCQ FLNIYVPKEA KNCPVLIFIH GGSFTGGSSN
     EAHINGENFA KNGVIFVAMN YRLNAFGFCS HPDLTDENGV CGNFGLFDQY AAIKWVRENI
     EAFGGNPNNI VLSGQSAGAM SVDIHLSNPL CKGWFSAAIM MSGGGLQRFL AKPLTPEKTR
     AFWDNIIENA GVKSIAELKK ADKEVLYRAW DKACKEDKLK SMLYTLPVCD GKIITQSNFN
     NRTIPQMPKI IGITKNDMVP AVLQAIDKKW VSCDKNSDCY IYYFARSLPG DEKGAWHSSD
     LLYAFSTLDK NWRPFEAVDY KISNQLAKSF IAFAKNGNPN CNEIPVWKPG TAKVMTFCEN
     TRPAHWNIPQ LLKNTFIGGA SI
//