ID R6QT16_9FIRM Unreviewed; 389 AA.
AC R6QT16;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Trigger factor {ECO:0000256|ARBA:ARBA00016902};
DE EC=5.2.1.8 {ECO:0000256|ARBA:ARBA00013194};
DE AltName: Full=PPIase {ECO:0000256|ARBA:ARBA00029986};
GN ORFNames=BN606_01804 {ECO:0000313|EMBL:CDC39778.1};
OS Butyrivibrio sp. CAG:318.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Butyrivibrio; environmental samples.
OX NCBI_TaxID=1262761 {ECO:0000313|EMBL:CDC39778.1, ECO:0000313|Proteomes:UP000018075};
RN [1] {ECO:0000313|EMBL:CDC39778.1, ECO:0000313|Proteomes:UP000018075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:318 {ECO:0000313|Proteomes:UP000018075};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC ChEBI:CHEBI:83834; EC=5.2.1.8;
CC Evidence={ECO:0000256|ARBA:ARBA00000971};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC39778.1}.
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DR EMBL; CBFF010000073; CDC39778.1; -; Genomic_DNA.
DR AlphaFoldDB; R6QT16; -.
DR STRING; 1262761.BN606_01804; -.
DR Proteomes; UP000018075; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:InterPro.
DR Gene3D; 3.10.50.40; -; 1.
DR Gene3D; 1.10.3120.10; Trigger factor, C-terminal domain; 1.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR001179; PPIase_FKBP_dom.
DR InterPro; IPR005215; Trig_fac.
DR InterPro; IPR008880; Trigger_fac_C.
DR InterPro; IPR037041; Trigger_fac_C_sf.
DR InterPro; IPR027304; Trigger_fact/SurA_dom_sf.
DR PANTHER; PTHR30560; TRIGGER FACTOR CHAPERONE AND PEPTIDYL-PROLYL CIS/TRANS ISOMERASE; 1.
DR PANTHER; PTHR30560:SF3; TRIGGER FACTOR-LIKE PROTEIN TIG, CHLOROPLASTIC; 1.
DR Pfam; PF00254; FKBP_C; 1.
DR Pfam; PF05698; Trigger_C; 1.
DR PIRSF; PIRSF003095; Trigger_factor; 1.
DR SUPFAM; SSF54534; FKBP-like; 1.
DR SUPFAM; SSF109998; Triger factor/SurA peptide-binding domain-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:CDC39778.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018075};
KW Rotamase {ECO:0000256|ARBA:ARBA00023110}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..389
FT /note="Trigger factor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039002827"
FT DOMAIN 99..182
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|Pfam:PF00254"
FT DOMAIN 211..369
FT /note="Trigger factor C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05698"
SQ SEQUENCE 389 AA; 44069 MW; C53B6A8FD8DF1235 CRC64;
MKKRLMAAGL VVLMAATAFT GCSKVKKIDD STEATTAEAE TMARVDVDVD IPDFSSYVTL
GDYTGIDIDV DSAEVTDKQL EQAKQNVIKN KTTQEHVTDR KVQDKDKIHL QYTGYLDDKA
FDGGSTGKDG TDYTIGGNYI PTLNDQLIGL ECGKEYSLNC KFPDNYGKEE LNGKDVVFKV
TVDYIYGDDI VPEWNDDFIN TITEGKYTTT ADYEAYMKES LKSSNESKQN ESYRAALWAK
IIDNTKISEY PQDKHDEVYN QFYEYMVNSY KSMATKYSMK YEDVLKAYGI TEDDIKKTCE
EQAKSQLEYC MVAYEIASKE DIELSDDEYN EMAEKYAKYV GYSSIADMQE AMSQQYLYDS
FLISKVSDYL SDKNNMVVKD ATEATTAAE
//
