ID R6R3E2_9FIRM Unreviewed; 371 AA.
AC R6R3E2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=HTH lacI-type domain-containing protein {ECO:0000259|PROSITE:PS50932};
GN ORFNames=BN652_00348 {ECO:0000313|EMBL:CDC43423.1};
OS Firmicutes bacterium CAG:424.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263022 {ECO:0000313|EMBL:CDC43423.1, ECO:0000313|Proteomes:UP000018167};
RN [1] {ECO:0000313|EMBL:CDC43423.1, ECO:0000313|Proteomes:UP000018167}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:424 {ECO:0000313|Proteomes:UP000018167};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC43423.1}.
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DR EMBL; CBFI010000021; CDC43423.1; -; Genomic_DNA.
DR AlphaFoldDB; R6R3E2; -.
DR Proteomes; UP000018167; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000018167};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..62
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 371 AA; 41949 MW; CB14B2E028798256 CRC64;
MRKKVTSTDI AKAAGVSQAT VSMVLNKKYN VSFSKETIQK VEQAARDMGY TIPKRRSQKS
QKNSRLIVVF CPTLTNPYYV MLLQGIETVA KEKGYGVFVC NTQRELKMEE QYLKMMHSVS
PAGIIYTCNP SEAFMEQVEE IAGKIPLVVI SNRERVKVDA INQDNTKVGS LMARHLLNLG
HREVAFIAPP LTKRQEQRSR RVEGFVREYE KKGLSQSVII KAADDIWDEV LPSVDSEYRI
GYTLTKELLA EKRKVTAIAG LNDMIAFGII DALQEEKLKV PGDVSVIGCD NIIFGRMSQM
SLTTIEHFVP LKGRDACDII MKKIESAHNT YSDTEPTSTY HIEYEPKLIV RKTTAYVNSK
RKKKKGKKKI N
//
