ID   R6RPE9_9FIRM            Unreviewed;       461 AA.
AC   R6RPE9;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Sortase SrtB family {ECO:0000313|EMBL:CDC49520.1};
GN   ORFNames=BN788_00038 {ECO:0000313|EMBL:CDC49520.1};
OS   [Eubacterium] siraeum CAG:80.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Oscillospiraceae incertae sedis.
OX   NCBI_TaxID=1263080 {ECO:0000313|EMBL:CDC49520.1, ECO:0000313|Proteomes:UP000018142};
RN   [1] {ECO:0000313|EMBL:CDC49520.1, ECO:0000313|Proteomes:UP000018142}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:80 {ECO:0000313|Proteomes:UP000018142};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC49520.1}.
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DR   EMBL; CBFJ010000222; CDC49520.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6RPE9; -.
DR   Proteomes; UP000018142; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd05826; Sortase_B; 1.
DR   Gene3D; 2.40.260.10; Sortase; 1.
DR   InterPro; IPR005754; Sortase.
DR   InterPro; IPR023365; Sortase_dom-sf.
DR   InterPro; IPR009835; SrtB.
DR   NCBIfam; TIGR03064; sortase_srtB; 1.
DR   Pfam; PF04203; Sortase; 1.
DR   SUPFAM; SSF63817; Sortase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018142};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        139..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          33..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        266
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT   ACT_SITE        376
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ   SEQUENCE   461 AA;  52426 MW;  E37C874260BBD8A8 CRC64;
     MESDNKFEND TGGMSVDEII ADIDRKTANA AALEENSVGV TPEGENEMSD EQAAVSADEA
     DTAAEHIPVD DESTIDELSG ADEMSDGQEA LEEKSAELAE EANADVTAKI EKKPNFFYRI
     VRGIIPWKGD DTGLVIRKII FIVAFIVFLA TAIPLLADIL SMYKDEQVSK GISQMYHLDA
     NTDVPENNKD ILPSFKKLLE INPDTVGYIK IDGTLVDYPV VKGTDNDYYL THDFYKNESR
     SGTVMMDYRN KVTADGHSGN LVLYGHNMAV GTFFAPLNEY WRTMYDSYDE PSKSFYKEHP
     VIRFDTLYEQ AEWKVFGFGI FNVAESRGEV YEYNQKRDFT SEDDFNDYII NIMDRSDIFT
     DVDLKYGDDI LTLSTCCWPY EGSGDTVRLA IFARKIRKGE SDSVDVEKAV GNPYVRRWQW
     VYDKVSGGYD WFQSTWDRRK LLSYDAEDAK RDNYSFPDKT D
//