ID R6RRY1_9FIRM Unreviewed; 383 AA.
AC R6RRY1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=THUMP domain-containing protein {ECO:0000259|PROSITE:PS51165};
GN ORFNames=BN652_02061 {ECO:0000313|EMBL:CDC48074.1};
OS Firmicutes bacterium CAG:424.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263022 {ECO:0000313|EMBL:CDC48074.1, ECO:0000313|Proteomes:UP000018167};
RN [1] {ECO:0000313|EMBL:CDC48074.1, ECO:0000313|Proteomes:UP000018167}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:424 {ECO:0000313|Proteomes:UP000018167};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC48074.1}.
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DR EMBL; CBFI010000097; CDC48074.1; -; Genomic_DNA.
DR AlphaFoldDB; R6RRY1; -.
DR Proteomes; UP000018167; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000018167};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 45..156
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 383 AA; 43680 MW; 38D2523270F39C3A CRC64;
MKTFELIAPC HFGLEAVLKR EIQDLGYEIS EVEDGKVTFL GDAEAIVRAN IFLRTTERIL
LKVGKIKAVT FEELFEKTKA LPWEDYIPVD GKFWVAKANS VKSQLFSPSD IQSIMKKAMV
ERLKSVYHVG WFEEDGPSYP IRVAFMKDVA TIGIDTTGVS LHKRGYRQLT SKAPITETLA
AALLKLTPWN KDRILVDPFC GSGTFPIEAA MMAANIAPGM NRSFLSEDWK NLISRKHWYN
IHDEANDLVN LDIETDIQGY DLDGEIIKAA RENARLAGVE KLIHFQQRDV KDLSHPKKYG
FVVTNPPYGE RIEERENLPA LYETIGKSYE GLDSWSMYLI TAYADAERYI GRKADKNRKI
YNGMMKTYFY QFLGPKPPKK SRV
//
