ID R6TDP2_9FIRM Unreviewed; 382 AA.
AC R6TDP2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Cell wall hydrolase SleB {ECO:0000313|EMBL:CDC67819.1};
GN ORFNames=BN714_01141 {ECO:0000313|EMBL:CDC67819.1};
OS Ruminococcus sp. CAG:57.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1262962 {ECO:0000313|EMBL:CDC67819.1, ECO:0000313|Proteomes:UP000018131};
RN [1] {ECO:0000313|EMBL:CDC67819.1, ECO:0000313|Proteomes:UP000018131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:57 {ECO:0000313|Proteomes:UP000018131};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC67819.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CBFS010000256; CDC67819.1; -; Genomic_DNA.
DR AlphaFoldDB; R6TDP2; -.
DR Proteomes; UP000018131; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.2520; Cell wall hydrolase SleB, domain 1; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR011105; Cell_wall_hydrolase_SleB.
DR InterPro; IPR003646; SH3-like_bac-type.
DR InterPro; IPR042047; SleB_dom1.
DR Pfam; PF07486; Hydrolase_2; 1.
DR Pfam; PF08239; SH3_3; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CDC67819.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018131};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 153..203
FT /note="SH3b"
FT /evidence="ECO:0000259|Pfam:PF08239"
FT DOMAIN 281..371
FT /note="Cell wall hydrolase SleB"
FT /evidence="ECO:0000259|Pfam:PF07486"
FT REGION 227..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..247
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 382 AA; 41600 MW; 25AE1A0DEAA0CB2A CRC64;
MKTVCVQTVG KGNVIKMKQK KTEDSIKRTA KPSVRKVGTM LGSGALAVLM IGTVSIFALT
SGNNEAQKDT KAAITNTKTT SVTEAETERD ETYTSMNTVT WRKAGISEYK MAQAESETTT
SAKATTTKKT ETTKNAAKET KVNNVTMVAT EIVNVREKAD KNSEIEAIVA ADEEVIVTAE
TSDGWYKVTY GDYSGYVMKD YLKKAEVTTT SAAKSETTTA AKKFETKKTT TTKAKTTKSE
TKKTETKKAT TSSSNSSVIS YTDEEFDMLC YVLQGEVGNC SEQSKIAVAN VIINRVKTGR
FGSSISDVLT APNQFTAING YYSGRNKPTQ NTIDCAKRAL NGEDNSNGAV YYYAPQYCGG
STASWFESLT FCMELDGQRY FK
//
