ID R6UBP9_9FIRM Unreviewed; 316 AA.
AC R6UBP9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Methylenetetrahydrofolate--tRNA-(Uracil-5-)-methy ltransferase TrmFO {ECO:0000313|EMBL:CDC68182.1};
GN ORFNames=BN503_01168 {ECO:0000313|EMBL:CDC68182.1};
OS Oscillibacter sp. CAG:155.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Oscillibacter; environmental samples.
OX NCBI_TaxID=1262910 {ECO:0000313|EMBL:CDC68182.1, ECO:0000313|Proteomes:UP000017942};
RN [1] {ECO:0000313|EMBL:CDC68182.1, ECO:0000313|Proteomes:UP000017942}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:155 {ECO:0000313|Proteomes:UP000017942};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC68182.1}.
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DR EMBL; CBFT010000044; CDC68182.1; -; Genomic_DNA.
DR AlphaFoldDB; R6UBP9; -.
DR Proteomes; UP000017942; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0047151; F:tRNA (uracil(54)-C5)-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR002218; MnmG-rel.
DR InterPro; IPR040131; MnmG_N.
DR InterPro; IPR004417; TrmFO.
DR NCBIfam; TIGR00137; gid_trmFO; 1.
DR PANTHER; PTHR11806; GLUCOSE INHIBITED DIVISION PROTEIN A; 1.
DR PANTHER; PTHR11806:SF2; METHYLENETETRAHYDROFOLATE--TRNA-(URACIL-5-)-METHYLTRANSFERASE TRMFO; 1.
DR Pfam; PF01134; GIDA; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW NAD {ECO:0000256|ARBA:ARBA00023027}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Reference proteome {ECO:0000313|Proteomes:UP000017942};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CDC68182.1};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 11..246
FT /note="MnmG N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01134"
SQ SEQUENCE 316 AA; 35353 MW; 3CF51608F292A563 CRC64;
MTEIPKGEVV IASGPLTSDA LAQRLGELLG EDTALHFYDA AAPLVSAESV DMNYAWMGSR
YDKGTADYVN CPMNQEEYDA FWQALTTAEE APVHGFEDGK VFEGCMPVEV MARRGHDTLL
YGPLKSRGLD DPRTGRWPYA VVQLRRDNAD GTVYNLVGFQ THLRFPEQRR VFSMIPALHD
AEFLRYGVMH RNTFLNSPRL LDRYYRLKKE PRISFAGQMT GVEGYVESAA SGFLVGVETA
RRLQGKPPVD FPQETAIGAL GLYVSNQSVT VFQPMNINFG IMPPLDHRVK GKRNKNAELS
QRSLTIIDGL REEVLS
//
