ID R6UDW5_9CLOT Unreviewed; 679 AA.
AC R6UDW5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 10-APR-2019, entry version 20.
DE RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN ORFNames=BN818_00947 {ECO:0000313|EMBL:CDC80284.1};
OS Clostridium sp. CAG:964.
OC Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC Clostridium; environmental samples.
OX NCBI_TaxID=1262848 {ECO:0000313|EMBL:CDC80284.1, ECO:0000313|Proteomes:UP000018136};
RN [1] {ECO:0000313|EMBL:CDC80284.1, ECO:0000313|Proteomes:UP000018136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:964 {ECO:0000313|Proteomes:UP000018136};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units
RT of genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC system. {ECO:0000256|RuleBase:RU362098}.
CC -!- SUBCELLULAR LOCATION: Cell membrane
CC {ECO:0000256|RuleBase:RU362098}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC {ECO:0000256|RuleBase:RU362098}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC of feature annotation. {ECO:0000256|RuleBase:RU362098}.
CC -!- CAUTION: The sequence shown here is derived from an
CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC preliminary data. {ECO:0000313|EMBL:CDC80284.1}.
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DR EMBL; CBFZ010000050; CDC80284.1; -; Genomic_DNA.
DR Proteomes; UP000018136; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR CDD; cd01879; FeoB; 1.
DR InterPro; IPR003373; Fe2_transport_prot-B.
DR InterPro; IPR011640; Fe2_transport_prot_B_C.
DR InterPro; IPR041069; FeoB_Cyto.
DR InterPro; IPR030389; G_FEOB_dom.
DR InterPro; IPR011642; Gate_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF07664; FeoB_C; 1.
DR Pfam; PF17910; FeoB_Cyto; 1.
DR Pfam; PF02421; FeoB_N; 1.
DR Pfam; PF07670; Gate; 2.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00437; feoB; 1.
DR PROSITE; PS51711; G_FEOB; 1.
PE 3: Inferred from homology;
KW Complete proteome {ECO:0000313|Proteomes:UP000018136};
KW GTP-binding {ECO:0000256|RuleBase:RU362098};
KW Ion transport {ECO:0000256|RuleBase:RU362098};
KW Iron {ECO:0000256|RuleBase:RU362098};
KW Iron transport {ECO:0000256|RuleBase:RU362098};
KW Membrane {ECO:0000256|RuleBase:RU362098};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW Reference proteome {ECO:0000313|Proteomes:UP000018136};
KW Transmembrane {ECO:0000256|RuleBase:RU362098};
KW Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW Transport {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 284 307 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 349 369 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 438 455 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 461 480 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 520 542 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 609 631 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 652 678 Helical. {ECO:0000256|RuleBase:RU362098}.
FT DOMAIN 3 165 FeoB-type G. {ECO:0000259|PROSITE:
FT PS51711}.
SQ SEQUENCE 679 AA; 74570 MW; B76B53668D257BBE CRC64;
MAEKIIALAG NPNVGKSTLF NALTGLKQHT GNWTGKTVSS AFGKYTYSND KYTVADLPGT
YSLLVSSKEE AQARNFLLEN RPDAVVVVVD ATCLERNLNL VLQILEITDK VVVCVNLLDE
AAKKKIEVNI KQLSQCLGVP VVGMCAKSGK GIKQLKEAVA NIIQSKTEIS PVKIEYSREI
EHSISKLLPI FDSLDISSKL KRCYALRLLE NDDYIKSKLT DHSTELSAVL TKLTQTDNKE
SIRDNIVNAI MKKCEYIFKK AVTLHNPSCN MRDRKIDKIL TSRLTGIPIM LLLLALIFWI
TIVGANYPSQ WLSRLFDWLC GVITGALKYI NTPPVIVSLL MDGIYKTTAW VVAVMLPPMA
IFFPLFTLLE DLGYLPRIAF NMDSMFKGAG CHGKQCLTMC MGIGCNACGV TGCRIIDSPR
ERLIAIITNS FMPCNGRFPA IIAIITVFFA GTAAAPLNSL LTALILMLVI LLGVFATMGV
SKLLSLTLLK GEASSFTLEL PPYRSPQIGK IIVRSILDRT LFVLGRAVVV AAPAGLIIWL
LANIEIGNTS LISYATNFLD PFARILGMDG IILAAFILGF PANEIVIPIM IMLYTNTGVL
TDADSLSQML SLFTANGWTV TTALCVIVFY LMHFPCSTTC ISIYKETKSL KWTLVSFFTP
LLCGFLLCFI ISTVSNIFF
//
