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Database: UniProt
Entry: R6UDW5_9CLOT
LinkDB: R6UDW5_9CLOT
Original site: R6UDW5_9CLOT 
ID   R6UDW5_9CLOT            Unreviewed;       679 AA.
AC   R6UDW5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   10-APR-2019, entry version 20.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=BN818_00947 {ECO:0000313|EMBL:CDC80284.1};
OS   Clostridium sp. CAG:964.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium; environmental samples.
OX   NCBI_TaxID=1262848 {ECO:0000313|EMBL:CDC80284.1, ECO:0000313|Proteomes:UP000018136};
RN   [1] {ECO:0000313|EMBL:CDC80284.1, ECO:0000313|Proteomes:UP000018136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:964 {ECO:0000313|Proteomes:UP000018136};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA   Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA   Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA   Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA   Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA   Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA   Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA   Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA   MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA   Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units
RT   of genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CDC80284.1}.
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DR   EMBL; CBFZ010000050; CDC80284.1; -; Genomic_DNA.
DR   Proteomes; UP000018136; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000018136};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018136};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    284    307       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    349    369       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    438    455       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    461    480       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    520    542       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    609    631       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    652    678       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        3    165       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   679 AA;  74570 MW;  B76B53668D257BBE CRC64;
     MAEKIIALAG NPNVGKSTLF NALTGLKQHT GNWTGKTVSS AFGKYTYSND KYTVADLPGT
     YSLLVSSKEE AQARNFLLEN RPDAVVVVVD ATCLERNLNL VLQILEITDK VVVCVNLLDE
     AAKKKIEVNI KQLSQCLGVP VVGMCAKSGK GIKQLKEAVA NIIQSKTEIS PVKIEYSREI
     EHSISKLLPI FDSLDISSKL KRCYALRLLE NDDYIKSKLT DHSTELSAVL TKLTQTDNKE
     SIRDNIVNAI MKKCEYIFKK AVTLHNPSCN MRDRKIDKIL TSRLTGIPIM LLLLALIFWI
     TIVGANYPSQ WLSRLFDWLC GVITGALKYI NTPPVIVSLL MDGIYKTTAW VVAVMLPPMA
     IFFPLFTLLE DLGYLPRIAF NMDSMFKGAG CHGKQCLTMC MGIGCNACGV TGCRIIDSPR
     ERLIAIITNS FMPCNGRFPA IIAIITVFFA GTAAAPLNSL LTALILMLVI LLGVFATMGV
     SKLLSLTLLK GEASSFTLEL PPYRSPQIGK IIVRSILDRT LFVLGRAVVV AAPAGLIIWL
     LANIEIGNTS LISYATNFLD PFARILGMDG IILAAFILGF PANEIVIPIM IMLYTNTGVL
     TDADSLSQML SLFTANGWTV TTALCVIVFY LMHFPCSTTC ISIYKETKSL KWTLVSFFTP
     LLCGFLLCFI ISTVSNIFF
//
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