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Database: UniProt
Entry: R6UWE7_9FIRM
LinkDB: R6UWE7_9FIRM
Original site: R6UWE7_9FIRM 
ID   R6UWE7_9FIRM            Unreviewed;       703 AA.
AC   R6UWE7;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   03-JUL-2019, entry version 25.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=BN746_02980 {ECO:0000313|EMBL:CDC84461.1};
OS   Erysipelotrichaceae bacterium CAG:64.
OC   Bacteria; Firmicutes; Erysipelotrichia; Erysipelotrichales;
OC   Erysipelotrichaceae; environmental samples.
OX   NCBI_TaxID=1262981 {ECO:0000313|EMBL:CDC84461.1, ECO:0000313|Proteomes:UP000018179};
RN   [1] {ECO:0000313|EMBL:CDC84461.1, ECO:0000313|Proteomes:UP000018179}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:64 {ECO:0000313|Proteomes:UP000018179};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA   Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA   Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA   Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA   Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA   Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA   Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA   Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA   MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA   Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units
RT   of genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CDC84461.1}.
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DR   EMBL; CBGA010000092; CDC84461.1; -; Genomic_DNA.
DR   Proteomes; UP000018179; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000018179};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    280    301       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    339    363       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    418    443       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    449    470       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    507    528       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    649    669       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    676    699       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        2    164       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   703 AA;  79416 MW;  4F461926CB56E6AA CRC64;
     MNYHVAFVGN PNVGKSAWIN ALSNADFKVG NWPGVTVEKK EANVCWGGDS YHIIDLPGTY
     SLTNNGNEES ITAAYLQSQQ VDLIVNVLDA TNLQRNLMLT LFLRELQIPM LLIFNFMDEV
     KDYGIHIDTA ALSRRLGMEI LAYSAFDRRH YREVRQAIQR QVEQRTVFYH PLLNEEEDEI
     YTSLYTYIEQ HGPSHAEADA RLLHHLAMGC MREDVLVMKQ LEAWHMDPVV LQKLCRDMNE
     ENVRAGYCRA VESLMHNVVQ DPKKRYAKSE RIDAFVLHKW LGLPLFLLVF SFLLLFVFQA
     SAPLNDYIGY LLQDVLARYV SFALQWAPHV LRQFLLQGIL AGVGGVLVFV PLMALLYFVL
     SLLEESGYMA RIAFLLDRLM NSFHLSGKSF VSLMLGFGCN VPAIYATRTL DNEQQKRLTA
     LLVPFMSCGA RLPVYVLFAS AFFPDKAALM MLSIYGIGIL LALVLALIAS RFPIFHDDAM
     LVLELPPYRL PSLRVVLHKV REEVKSYVRK ACGIVLWAMV ILWGLTYFPG GSVEDSYLAQ
     GAKLVQPIFA PLGFGDRWEC VAALPGGIIA KETIVGFLDT VLQPAVHEEA TTVNISEDIR
     DILYKGGTAL KESATFFLHT DVAVKPQGDA QVSHIRALWT SRDAGIRSFS FMVYVLLSIP
     CIMTLQAVYH EYGKKLLFLT LTVMLLVPYL VSLFIFQFFS LFL
//
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