ID   R6V9H4_9FIRM            Unreviewed;       332 AA.
AC   R6V9H4;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Aminoacyl-histidine dipeptidase {ECO:0000313|EMBL:CDC94908.1};
GN   ORFNames=BN635_00121 {ECO:0000313|EMBL:CDC94908.1};
OS   Roseburia sp. CAG:380.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=1262946 {ECO:0000313|EMBL:CDC94908.1, ECO:0000313|Proteomes:UP000017909};
RN   [1] {ECO:0000313|EMBL:CDC94908.1, ECO:0000313|Proteomes:UP000017909}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:380 {ECO:0000313|Proteomes:UP000017909};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC94908.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CBGD010000179; CDC94908.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6V9H4; -.
DR   STRING; 1262946.BN635_00121; -.
DR   Proteomes; UP000017909; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR002933; Peptidase_M20.
DR   InterPro; IPR011650; Peptidase_M20_dimer.
DR   InterPro; IPR001160; Peptidase_M20C.
DR   PANTHER; PTHR43501; CYTOSOL NON-SPECIFIC DIPEPTIDASE; 1.
DR   PANTHER; PTHR43501:SF1; CYTOSOL NON-SPECIFIC DIPEPTIDASE; 1.
DR   Pfam; PF07687; M20_dimer; 1.
DR   Pfam; PF01546; Peptidase_M20; 1.
DR   PRINTS; PR00934; XHISDIPTASE.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017909}.
FT   DOMAIN          59..140
FT                   /note="Peptidase M20 dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF07687"
SQ   SEQUENCE   332 AA;  36868 MW;  D2147C4AFFB77838 CRC64;
     MLGAAAIDCS DLRSRIMLNL DSEDEGHLLV SCAGGVTAEA HLPVKWERTD GEQIRLTVTG
     LMGGHSGVEI DKGRANACRL LGRTLFTLKD SCHFRLLRLD GGLKDNAIPR EATALLLCED
     GDGERVIREL EKVYQNEYRQ TDPSICLVWE STGTKMGQRA MTQHSTDDVI AALVNLPGGI
     QRMSFDIPGL VQTSLNLGIM ITREEEVSFS FSVRSSIGTE KEELVQRIRC LMEALGGSVT
     CTGAYPAWEY REDSPLRELM IQIYEEQYGE KPVVEALHAG VECGLFAGKL QGLDCVSFGP
     DMDDIHTPKE SMNVDSVRRT WDYVIEILRR LR
//