ID R6VW54_9BACT Unreviewed; 400 AA.
AC R6VW54;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700};
GN ORFNames=BN576_00878 {ECO:0000313|EMBL:CDC98694.1};
OS Alistipes sp. CAG:268.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC Alistipes.
OX NCBI_TaxID=1262693 {ECO:0000313|EMBL:CDC98694.1, ECO:0000313|Proteomes:UP000018329};
RN [1] {ECO:0000313|EMBL:CDC98694.1, ECO:0000313|Proteomes:UP000018329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:268 {ECO:0000313|Proteomes:UP000018329};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|PIRNR:PIRNR005700}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC98694.1}.
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DR EMBL; CBGE010000163; CDC98694.1; -; Genomic_DNA.
DR AlphaFoldDB; R6VW54; -.
DR STRING; 1262693.BN576_00878; -.
DR Proteomes; UP000018329; Unassembled WGS sequence.
DR GO; GO:0070005; F:cysteine-type aminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR004134; Peptidase_C1B.
DR PANTHER; PTHR12411:SF741; CATHEPSIN K; 1.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR Pfam; PF03051; Peptidase_C1_2; 1.
DR PIRSF; PIRSF005700; PepC; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700,
KW ECO:0000313|EMBL:CDC98694.1}; Hydrolase {ECO:0000256|PIRNR:PIRNR005700};
KW Protease {ECO:0000256|PIRNR:PIRNR005700};
KW Reference proteome {ECO:0000313|Proteomes:UP000018329};
KW Signal {ECO:0000256|SAM:SignalP};
KW Thiol protease {ECO:0000256|PIRNR:PIRNR005700}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..400
FT /note="Aminopeptidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004422324"
FT ACT_SITE 53
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 335
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 356
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
SQ SEQUENCE 400 AA; 45127 MW; 06DBE8765E26B3D0 CRC64;
MKRLMLSAVA FCLALTAAAQ TDTNNDSAPG YQFTDVKVIE TTPVKDQSRS GTCWCFSTLS
FLESEIIKAG GEPMHLSEMW IVRHSFMDKA EKYVRMHGTL NFAEGGAAHD VTEGIREHGI
VPFEVYPGLN YGTTKPDFHE ISEVLKSYLD AVIRAAGNKP LSTAWKRGFN AILDEYFGVL
PETFTYEGKE YTPESFAASL PISMDDYVDV SSFTHHPFYS RFIIEVPDNW MWAEVYNVPL
EEMMQIVDNA LENGYTVAWG TDVSEKGFSR TKGIGVIPEA DLEGMSGTEA ERWGKLTEQE
KEAALYKFDK PGKERTITQE MRQTSFDNWE TTDDHGMLIM GLAKDQNGTP YYKVQNSWNT
VAPYDGFWYF SKPFVAYKTT SLMVNKNAIP KEIAKKLGLK
//
