ID   R6VX39_9BACT            Unreviewed;       946 AA.
AC   R6VX39;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=GHMP kinase protein {ECO:0000313|EMBL:CDC98999.1};
GN   ORFNames=BN673_00316 {ECO:0000313|EMBL:CDC98999.1};
OS   Prevotella sp. CAG:474.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=1262926 {ECO:0000313|EMBL:CDC98999.1, ECO:0000313|Proteomes:UP000018116};
RN   [1] {ECO:0000313|EMBL:CDC98999.1, ECO:0000313|Proteomes:UP000018116}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:474 {ECO:0000313|Proteomes:UP000018116};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GHMP kinase family.
CC       {ECO:0000256|ARBA:ARBA00038121}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC98999.1}.
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DR   EMBL; CBGF010000064; CDC98999.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6VX39; -.
DR   STRING; 1262926.BN673_00316; -.
DR   Proteomes; UP000018116; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR   Gene3D; 3.30.230.120; -; 1.
DR   InterPro; IPR012887; Fucokinase.
DR   InterPro; IPR001174; Galkinase.
DR   InterPro; IPR013750; GHMP_kinase_C_dom.
DR   InterPro; IPR036554; GHMP_kinase_C_sf.
DR   InterPro; IPR006204; GHMP_kinase_N_dom.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   PANTHER; PTHR32463; L-FUCOSE KINASE; 1.
DR   PANTHER; PTHR32463:SF0; L-FUCOSE KINASE; 1.
DR   Pfam; PF07959; Fucokinase; 2.
DR   Pfam; PF08544; GHMP_kinases_C; 1.
DR   Pfam; PF00288; GHMP_kinases_N; 1.
DR   PRINTS; PR00960; LMBPPROTEIN.
DR   SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CDC98999.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018116};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          74..249
FT                   /note="L-fucokinase"
FT                   /evidence="ECO:0000259|Pfam:PF07959"
FT   DOMAIN          257..427
FT                   /note="L-fucokinase"
FT                   /evidence="ECO:0000259|Pfam:PF07959"
FT   DOMAIN          701..763
FT                   /note="GHMP kinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00288"
FT   DOMAIN          843..922
FT                   /note="GHMP kinase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08544"
SQ   SEQUENCE   946 AA;  105973 MW;  E1C8E8A8A9F15D59 CRC64;
     MKKLLSLPPN LVGCFHDITG LSDTEWFCTN DPVGRKLGSG GGTTWLLQAC YEAHGNGRSF
     DEWLAADRRL LLHAGGQSRR LPSYAPSGKI LTPIPVFRWE RGQRLSQDLL SLQVPLYQRI
     MNQAPEGLRT MIVSGDVYIR ATQALQPIPD ADVVCYGLWL GPEIAKDHGV FVSSRQTPTQ
     LKCMLQKPSM QTLGQLQKEH FYLTDIGVWL LSDRAVKVLM RRSMRDGEVT NYDMYGEFGC
     CLGTDPTIDD PEVNDLKVAI LPLPGGEFYH FGTSHEIVSS MLDIQNVVND QREIMHHSLK
     PHPSMFTQNS EVEIKITEHN QNLWIENSCV SAQWTIAHEN IITGVPRNQW KIELRPGQCV
     DIVPIGDESY AIRPYGFNDK FRGDITDGVT EYLGEPFTRW AEERGIDAAA IEGKDDLQSA
     RIFPVVDNIN DAGLVLRWML NEPYQQGGRV VWNEAQRLSA DEISAQANLR RLVEQRRENR
     AQNWSFLSHN YAHSVFYQVD LDDAAHEFAA NHIAEPTPLP ADEPLLTRIH DAMFRSELQR
     LNGKDGSESE GRAFSLLREG LTQTVLAEKQ HPRLSVYSDQ IVWGRSPVRI DIAGGWTDTP
     PFCLMEGGNV INLAIELNGQ PPLQTYVKPC RDHHIILRSI DLGASEVITT FEELRDFHHV
     GSPFSIPKAA LALAGFLPEY SAEQYQSLAQ QLAAFGCGIE VTLLSAIPAG SGLGTSSLLA
     STVLGAINDF CGLMWDKNEI GRRTLVLEQL LTTGGGWQDQ FGGLLQGIKL LQTGKGFDQN
     PVVRWLPSSL YTQPEYRACH LLYYTGITRT AKKILAEIVR RMFLNQHDEL ALLREMKQHT
     IDMFEAIQRE NFDEMGRLVR KTWQQNQLLD SGTNPAEVAR LTSLIDDLCL GYKLPGAGGG
     GYLYMVAKDP EAAARIKQIL RENRLNANAR FVDMSLSDKG LQISRS
//