ID R6W6N4_9BACT Unreviewed; 544 AA.
AC R6W6N4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Type I phosphodiesterase/nucleotide pyrophosphatase {ECO:0000313|EMBL:CDD05100.1};
GN ORFNames=BN725_01541 {ECO:0000313|EMBL:CDD05100.1};
OS Prevotella sp. CAG:592.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1262931 {ECO:0000313|EMBL:CDD05100.1, ECO:0000313|Proteomes:UP000018343};
RN [1] {ECO:0000313|EMBL:CDD05100.1, ECO:0000313|Proteomes:UP000018343}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:592 {ECO:0000313|Proteomes:UP000018343};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD05100.1}.
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DR EMBL; CBGI010000103; CDD05100.1; -; Genomic_DNA.
DR AlphaFoldDB; R6W6N4; -.
DR Proteomes; UP000018343; Unassembled WGS sequence.
DR GO; GO:0004035; F:alkaline phosphatase activity; IEA:InterPro.
DR CDD; cd16016; AP-SPAP; 1.
DR Gene3D; 3.30.1360.150; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR026263; Alkaline_phosphatase_prok.
DR InterPro; IPR002591; Phosphodiest/P_Trfase.
DR PANTHER; PTHR10151:SF120; BIS(5'-ADENOSYL)-TRIPHOSPHATASE; 1.
DR PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR Pfam; PF01663; Phosphodiest; 1.
DR PIRSF; PIRSF031924; Pi-irrepressible_AP; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|PIRSR:PIRSR031924-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000018343};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..544
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004422721"
FT ACT_SITE 83
FT /note="Phosphothreonine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR031924-50"
FT BINDING 104
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
FT BINDING 163..165
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
SQ SEQUENCE 544 AA; 60928 MW; D6B7C2FC914448A3 CRC64;
MKKTITVLAA LFLSCCGMQA QDGKSANLTF QRPRLVVGIV IDQMRWDYLY RYQQRYTEGG
FKRLLNQGYS FENTRIPYIP SVTAIGHTCI YTGSVPTIHG IAGNNFYKDG KKVYCTTDKT
VTPVGTKSES GQMSPRNLWV TTISDEMKLA TNGRSKVVGV SLKDRASILP AGHTPDGAFW
FDDETGNFVT STYYMDKLPA WVTRFNRERH AEKYLSEKWQ TIYPKDSYIE STADNTEYED
GIKAGEKALL PLDLPSLYKK YGYEIIRKTP FGNSITFDMA RAAIEGEHLG EDDDVDLLAV
SCSSTDYIGH QVGPNAVEIE DTYLRLDRSI ADFLNYLDEK VGKGNYLVFL TADHGAMNNA
RFLQDRRIPA GAWSNSEVAD RLNARLSETF PGCGKIVSEV MNYQVFFDIA RIRQLHLDYD
RIKQCVVDEL LTDSSVHYAC DMNKVMTATI PDDVKRRIIN GYCHGRSGDV QIVLKPGFYA
HSMKGTDHGA WTPYDTHIPL IFMGWGVSHG STTELTEMTD ITPTIAALLH VQAPSGCVGK
PLLP
//
