ID R6WEY1_9FIRM Unreviewed; 423 AA.
AC R6WEY1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=PDZ domain-containing protein {ECO:0000259|PROSITE:PS50106};
GN ORFNames=BN605_01359 {ECO:0000313|EMBL:CDD07965.1};
OS Dorea sp. CAG:317.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX NCBI_TaxID=1262873 {ECO:0000313|EMBL:CDD07965.1, ECO:0000313|Proteomes:UP000018262};
RN [1] {ECO:0000313|EMBL:CDD07965.1, ECO:0000313|Proteomes:UP000018262}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:317 {ECO:0000313|Proteomes:UP000018262};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD07965.1}.
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DR EMBL; CBGJ010000086; CDD07965.1; -; Genomic_DNA.
DR AlphaFoldDB; R6WEY1; -.
DR STRING; 1262873.BN605_01359; -.
DR Proteomes; UP000018262; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR22939:SF125; PROTEASE DO-LIKE 14-RELATED; 1.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000018262};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 44..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 328..381
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 72..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 423 AA; 45548 MW; 85DD6906BF119BE0 CRC64;
MDEQKNQEQP ELNEAPEEYS FLQEVIKDEA GGPKRLKAKI LRMIGLGFIF GIVACFSFCL
LYPVISEHLS GNPEEVTIPK DTEEEPEGEV TEAEKEKPEE EFAVMMDQLD EAARKVRKSV
AEIRVISPEG NSEKTVDSVE KLSGVIMADN GQELLILGQA PGGKSGEKIE IVLADETLHP
AALKMEDVNL DLCVYSINRA DISEKTWEKI SVAALGSSYA VQTGNIGILL GKPFGTEDAV
SYGKIISYEE KAKKADGEYG FIGVEAAGFS GGSGVIANLE GQIIGVISHS IFSDGTGAND
GRIYGYGISD IKGILELLSN GSLIPYVGIL GTDVTEEMSE QRGIPSGVYV DEIEADSPAM
EAGVQCGDVI TSINGESVSR MQFYNNQLMD QKEGDTLRLQ GFRKGAGGEY VDISFTVTVG
TKK
//
