ID   R6WNB2_9BACT            Unreviewed;       271 AA.
AC   R6WNB2;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Methylcobamide:CoM methyltransferase mtbA {ECO:0000313|EMBL:CDD05546.1};
GN   ORFNames=BN725_01954 {ECO:0000313|EMBL:CDD05546.1};
OS   Prevotella sp. CAG:592.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=1262931 {ECO:0000313|EMBL:CDD05546.1, ECO:0000313|Proteomes:UP000018343};
RN   [1] {ECO:0000313|EMBL:CDD05546.1, ECO:0000313|Proteomes:UP000018343}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:592 {ECO:0000313|Proteomes:UP000018343};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD05546.1}.
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DR   EMBL; CBGI010000169; CDD05546.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6WNB2; -.
DR   Proteomes; UP000018343; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:InterPro.
DR   CDD; cd03465; URO-D_like; 1.
DR   Gene3D; 3.20.20.210; -; 1.
DR   InterPro; IPR038071; UROD/MetE-like_sf.
DR   InterPro; IPR000257; Uroporphyrinogen_deCOase.
DR   PANTHER; PTHR47099; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR   PANTHER; PTHR47099:SF1; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR   Pfam; PF01208; URO-D; 1.
DR   SUPFAM; SSF51726; UROD/MetE-like; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:CDD05546.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018343};
KW   Transferase {ECO:0000313|EMBL:CDD05546.1}.
FT   DOMAIN          2..266
FT                   /note="Uroporphyrinogen decarboxylase (URO-D)"
FT                   /evidence="ECO:0000259|Pfam:PF01208"
SQ   SEQUENCE   271 AA;  29598 MW;  89AD52359D391B17 CRC64;
     MDLTVEAEAF GADIHFTEDA VPAVIGHLLN DADDIKALKV PSLKAARVPE YLKANLLSAR
     AINDRPVLGG CIGPFSLAGR LYDMSEIMVL IYQDPDAAHT LLAKCTEFIL KYCKALKMTG
     VDGVVMAEPA AGLMSDDDCK RFSSDYIRYI VGQVQDDSFS IVLHNCGNTG HCTKAMVATG
     AAAYHFGNKC DMRQVIKDVP PTALAMGNID PVSVFKEGTP EQMYETTTRL LQEMKEYPNF
     VLSSGCDTPP HTPMENIDAF FKALDDFDKT I
//