ID   R6WV75_9BACT            Unreviewed;       723 AA.
AC   R6WV75;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Alpha-1 2-mannosidase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BN576_00594 {ECO:0000313|EMBL:CDC97992.1};
OS   Alistipes sp. CAG:268.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC   Alistipes.
OX   NCBI_TaxID=1262693 {ECO:0000313|EMBL:CDC97992.1, ECO:0000313|Proteomes:UP000018329};
RN   [1] {ECO:0000313|EMBL:CDC97992.1, ECO:0000313|Proteomes:UP000018329}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:268 {ECO:0000313|Proteomes:UP000018329};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC97992.1}.
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DR   EMBL; CBGE010000131; CDC97992.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6WV75; -.
DR   STRING; 1262693.BN576_00594; -.
DR   Proteomes; UP000018329; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 1.20.1050.60; alpha-1,2-mannosidase; 1.
DR   Gene3D; 1.20.1610.10; alpha-1,2-mannosidases domains; 1.
DR   Gene3D; 3.30.2080.10; GH92 mannosidase domain; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR005887; GH92_a_mannosidase_put.
DR   InterPro; IPR041371; GH92_N.
DR   InterPro; IPR012939; Glyco_hydro_92.
DR   NCBIfam; TIGR01180; aman2_put; 1.
DR   PANTHER; PTHR12143; PEPTIDE N-GLYCANASE PNGASE -RELATED; 1.
DR   PANTHER; PTHR12143:SF39; SECRETED PROTEIN-RELATED; 1.
DR   Pfam; PF07971; Glyco_hydro_92; 1.
DR   Pfam; PF17678; Glyco_hydro_92N; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018329}.
FT   DOMAIN          4..229
FT                   /note="Glycosyl hydrolase family 92 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17678"
FT   DOMAIN          235..714
FT                   /note="Glycosyl hydrolase family 92"
FT                   /evidence="ECO:0000259|Pfam:PF07971"
SQ   SEQUENCE   723 AA;  82558 MW;  9ECF822D775D141D CRC64;
     MLGPYAQAPF GMVQLGPDNQ GDVWMGGYEY SIHNVSGFSH LHAWTMGGLM IMPTTADLAI
     GNPSTDSPYR GANAGYHSRI LKESETASPG YYSVYLYDHA VRAELTATTR CGVHRYTFPE
     RNESRILIDL LFPTEWDYGF RVRDARIARV SDTELEGYAD CQSGPWSWWN EYRLHFVIRF
     SRPFRRLDGW NEGRIEEDIR EITGKGDTGA YALFTTTEGE RITVCTGLSL VSIDQARLNM
     QTELGPLGYD FDRTARATRE QWNELLGRVE VTGGSERDRV KFYTNLYRAY AGKQTWNDVD
     GSYVDAEEHV RRVERGNMYG GDAFWNTYWN LNGLWSILSP RIVDDWVTTQ LEMFRHTGWT
     CKGPAGLEYS GIMEGSHETA LLVAACQKGI RSDREAVYEA VHKNVTVPGI NHPGGGNAGN
     PLLDVYDRFG YMPQEYGVVS KTLDYAYDDW CVAQLARAVG DRREARRLEA RAQNYRNVFH
     PEWKYVARRD STGGWDPAFD RFSNAGFIEG NSWQYSWYVP HDIPGLVELI GREEFNRRLE
     EGFERSERHN FAAHVFDRTM GQSAEFYINH GNEVNMCTPY LFNYSGKPWL AQRWARAILE
     RFYGETPYHG WEGDEDEGQM SAWYVMSAMG LFEMDGGCSA EPMVDLGSPL FEKITVRLDP
     DYYPGRTFTI EARNNSPENV YVQRAYLNGK RLSRPRIPFA AIAEGGTLLF EMGPEPAPDC
     YEE
//