ID R6XC21_9BACT Unreviewed; 631 AA.
AC R6XC21;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=ATP-dependent DNA helicase RecQ {ECO:0000313|EMBL:CDD19055.1};
GN ORFNames=BN655_01580 {ECO:0000313|EMBL:CDD19055.1};
OS Alistipes sp. CAG:435.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC Alistipes.
OX NCBI_TaxID=1262695 {ECO:0000313|EMBL:CDD19055.1, ECO:0000313|Proteomes:UP000017965};
RN [1] {ECO:0000313|EMBL:CDD19055.1, ECO:0000313|Proteomes:UP000017965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:435 {ECO:0000313|Proteomes:UP000017965};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD19055.1}.
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DR EMBL; CBGN010000088; CDD19055.1; -; Genomic_DNA.
DR AlphaFoldDB; R6XC21; -.
DR STRING; 1262695.BN655_01580; -.
DR Proteomes; UP000017965; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CDD19055.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 24..191
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 212..358
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 631 AA; 71515 MW; 02E8D0BADE768D41 CRC64;
MSPSEVLKEY WGYDGFRPMQ EEIITAALEG KDVLAIMPTG GGKSICFQVP GLMRDGITLV
VTPLIALMKD QVQNLNDRGV RALAIHAGMS RHEVDLALNN AAYGDYKFLY LSPERLGTQL
FRSYIDVLDV SFIVVDEAHC ISQWGYDFRP DYLRIGELRE RIDAPVIAVT ATATPSVAQD
IMERLGFKEK LLLKSGFERP NLSYIVRQVE DKYSQILNVC NGVPGTGIVY ARNRRKCEEL
SAFLMAQGVS ASFYHAGLGG QARAERQAAW KSGAVRVMVC TNAFGMGIDK PDVRFVVHYD
LPESPEAYFQ EAGRAGRDGK RSFAVQLWNS VDVRRAKQIE DVSFPSLEYI EDVYQKLHAF
FEIPYDTGMG RQLKFKIEDF CKRFGLQRAP AFYALKYLER TDHLTYSEEV DIPTKVRINV
DRKSLYDVEL ADQGQANVLE ALMRSYTGIF SFLQQIDEEY VARRAGQTVP QLRQSLYGLS
LAHVISYVPT DHSDVVVLHH DRLHPGNVNL MPSRYAMLRE SFHARAEAML EYVSETSECR
SRYLLRYFGQ TKAADCGTCD VCRARRAALP ARTLQQMTRR KLIEYIDEKD GEYSLEEIVA
EFGNPSGNHS PDYLDILRQL IDNGDVPMYI S
//
