ID   R6XFV7_9BACT            Unreviewed;       700 AA.
AC   R6XFV7;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Subtilisin-like serine protease {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BN655_02082 {ECO:0000313|EMBL:CDD15216.1};
OS   Alistipes sp. CAG:435.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC   Alistipes.
OX   NCBI_TaxID=1262695 {ECO:0000313|EMBL:CDD15216.1, ECO:0000313|Proteomes:UP000017965};
RN   [1] {ECO:0000313|EMBL:CDD15216.1, ECO:0000313|Proteomes:UP000017965}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:435 {ECO:0000313|Proteomes:UP000017965};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S8 family.
CC       {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD15216.1}.
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DR   EMBL; CBGN010000003; CDD15216.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6XFV7; -.
DR   STRING; 1262695.BN655_02082; -.
DR   Proteomes; UP000017965; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR032304; Peptidase_S8_N.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR   PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR   PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   Pfam; PF16361; Peptidase_S8_N; 1.
DR   PRINTS; PR00723; SUBTILISIN.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51892; SUBTILASE; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU01240};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW   ProRule:PRU01240};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}.
FT   DOMAIN          11..91
FT                   /note="Subtilase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16361"
FT   DOMAIN          124..395
FT                   /note="Peptidase S8/S53"
FT                   /evidence="ECO:0000259|Pfam:PF00082"
FT   ACT_SITE        131
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        164
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        359
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ   SEQUENCE   700 AA;  74889 MW;  74D274E17B40E6E4 CRC64;
     MIVKLTPEAA DAMEKGSALL SSVSESLGVK HAERLFPDAG EYEPLHRKCG LHQYYIVDFD
     SALPLAKAQE ILGSLDGVEA SEKRNIICRS ASTNDPGYAY LWEYSGRYSI NVEDAWKYTT
     GDPSVVVCVV DGGINLKHED LAWNCGSVNW NFVRNSSNII PEDHGCHVAG TIAGVRNNGK
     GLAGIAGGDY AAGKKGVTLM SAQVFQGNST ASSFQNAIVW GADNGAVISQ NSWGNDYDFN
     HDDVLSAYEK DYALRDRISS SMAAAIDYFI AYAGCDKDGN QKPGSPMKGG LVVFAAGNYG
     IANGVPASYA PVIAVGASGM TGRLSSFSNY GSWVDICAPG ESIYSCVASG SYGRLKGTSM
     ACPHVSGALA LLLSQFGGEG FTNENLKEVL LEGANASLIN YNGKAMGPYL DVMGSMRYGL
     SKYGRENNNP PVIETSYTGD FKFRQWESVS IPFTVSDPDG DNVEVTTDFE GRAKLVRGSK
     DPDVYNFEIL CELVSDFTPK KAKITATDVY GGTAVYEFAY QVIENHPPVV SEPINDVVLS
     GDGKMSAYLD GVFSDPDDEP LEYSAKISPD GVADVSISGD GKLVVAKKQN GLAVITVTAK
     DRLGAKISTD FKIVARDESY AVDYYPNPVR DFLNVRPGST AVVDVMVKIA STSGSVILEK
     KVSCNVFDPA RIDMSAFAPG EYKLGLTVGA DKYDYVIVKR
//