ID R6XXA4_9BACT Unreviewed; 637 AA.
AC R6XXA4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=ATP-dependent DNA helicase RecQ {ECO:0000313|EMBL:CDD20941.1};
GN ORFNames=BN769_00979 {ECO:0000313|EMBL:CDD20941.1};
OS Prevotella sp. CAG:732.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1262934 {ECO:0000313|EMBL:CDD20941.1, ECO:0000313|Proteomes:UP000018039};
RN [1] {ECO:0000313|EMBL:CDD20941.1, ECO:0000313|Proteomes:UP000018039}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:732 {ECO:0000313|Proteomes:UP000018039};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD20941.1}.
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DR EMBL; CBGP010000178; CDD20941.1; -; Genomic_DNA.
DR AlphaFoldDB; R6XXA4; -.
DR Proteomes; UP000018039; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CDD20941.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000018039}.
FT DOMAIN 26..194
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 218..364
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 637 AA; 73337 MW; 734FAF414CF89A5D CRC64;
MADKYQEILR TYWGYPDFRG IQREIIESIA AGKDTLGLMP TGGGKSITFQ VPALAQEGVC
IVITPLIALM KDQVLHLRER GILADAIYAD MSRSEIIQTL ENCIFGGVKI LYVSPERLSS
EIFQVKLRHM KVSFITVDEA HCISQWGYDF RPSYLRIADI RQMKPGTPVL ALTATATPAV
VDDIQDKLQF AEKNVFKMSF ERKNLAYIVR TVADKQNEMI HILQCVEGSA IVYARSRKRT
KEMAEVLSKS GIPATFYHAG LDPVVKDERQ KMWQDDEVRV MVATNAFGMG IDKPDVRMVI
HIDCPDSLEA YFQEAGRAGR DGNKAYAVLL YDAADERKLR KRIDDTFPDK EQIKDIYEHL
AYFFQIGVES GRGKTFEFDI EKFSYIYKYF PTKVDAALRI LEHCGYIHYE DNPDGKARLM
FNLERNDLYQ LENLHANEDE VITTLLRIYG GLFTDFVYID ESLVAHHADM SIQQVYFALK
NLAARHIIKF IPRRKIPYIT YLRDRIDGEK VIITPEAYEE RKEQFEKRIE SMIGYATTDY
ICRSRQLLRY FGESTQEDCH QCDVCLEHKD HDSVGKQMYE KAMEQIMALL KDGEKHFVTE
LQNFQLPSRQ VSDALEALVA ENKVHIDGAY FFALAED
//
